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Dietary supplement modifies gut microbiome—potential implications for bone marrow transplant patients
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Dietary supplement modifies gut microbiome—potential implications for bone marrow transplant patients

by Molly Chiu, Baylor College of Medicine Plasma metabolites in historic controls versus recipients of RPS. a, UMAP ordination of median-centered plasma metabolite levels revealed four distinct clusters of metabolites. b, UMAP ordination stratified according to clinical group (historic controls in blue or recipients of RPS in orange), with the largest divergence in overlap at engraftment....

Researchers develop new method to make bone marrow transplants safer and more effective
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Researchers develop new method to make bone marrow transplants safer and more effective

by University of Missouri Credit: Unsplash/CC0 Public Domain A groundbreaking process developed by researchers based in the Roy Blunt NextGen Precision Health Building is offering new hope in the fight against blood cancers, such as lymphoma and leukemia. A pair of researchers at the University of Missouri School of Medicine have developed a process for marking transplanted...

Bone marrow transplant may halt brain blood vessel disease in adults with sickle cell disease
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Bone marrow transplant may halt brain blood vessel disease in adults with sickle cell disease

by American Heart Association Credit: Pixabay/CC0 Public Domain Bone marrow transplants prevented or improved blood vessel disease in the brains of adults with sickle cell disease, according to preliminary research to be presented at the American Stroke Association’s International Stroke Conference 2023. The meeting, to be held in person in Dallas and virtually Feb. 8-10, 2023, is...

Bone marrow transplant: What is the impact of chemotherapy on the brain?
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Bone marrow transplant: What is the impact of chemotherapy on the brain?

by Institut du Cerveau (Paris Brain Institute)  Fig. 1: HSCT causes the accumulation of brain parenchymal donor macrophages that become resident and surveillant. Credit: DOI: 10.1038/s41591-022-01691-9 More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases. Before the cells are transplanted, the...

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Partial bone marrow transplant ‘rescues’ mice with cystic fibrosis

by La Jolla Institute for Immunology A partial bone marrow transplant helps these mice by introducing a population of healthy immune cells called monocytes. Credit: La Jolla Institute for Immunology Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow...