by Niigata University Aging is associated with increased susceptibility to periodontitis due to the reduced expression of DEL-1. Credit: Niigata UniversityResearchers from Niigata University and a University of Pennsylvania team have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to the development of therapeutic agents to...
TECHNISCHE UNIVERSITÄT DRESDEN IMAGE: AN ARTISTIC DEPICTION OF COMPUTER-AIDED STRUCTURE-BASED RATIONAL DESIGN. THE GREEN ARROWS SYMBOLIZE THE INNOVATIVE STRATEGY TO INTRODUCE NEW CHEMICAL PROPERTIES IN THE HYALURONIC ACID MOLECULE (GREEN AND RED STICKS) TO DEVELOP RATIONALLY ENGINEERED GAG (REGAG) MOLECULES THAT ACT AS HIJACKERS OF BONE REGENERATION BLOCKING PROTEINS. DICKKOPF-1, A PROTEIN BLOCKING BONE FORMATION,...
by University of Tsukuba Fig. 1. Isolation and characterization of CD73-EGFP+ cells from BM. (A) EGFP+ colonies containing EGFP− cells of primary BM cultures displayed typical MSC-like morphology at day 5 in culture. Scale bars 100 μm, insets 10 μm. (B) EGFP+ and EGFP− cell fractions were sorted by flow cytometry from passage 2 to 3 of a...
