by Australian National University Credit: Pixabay/CC0 Public DomainA protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU). The research is published in Science Advances. Bowel cancer claims more than 100 lives in Australia each week, yet around 90% of cases can be...
by South Australian Health and Medical Research Institute (SAHMRI) Schematic of orally-delivered EcN probiotic engineered to lyse and produce immunotherapeutic proteins in situ (top) and schematic of dosing regimen (bottom). Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-44776-4An international team of researchers from Adelaide and the United States has opened the door to non-stool-based bowel cancer detection...
by University of Glasgow Microscopic image of an intestinal lymph node involved by metastatic colon cancer (colonic adenocarcinoma). Credit: Shutterstock A mystery which has stumped bowel cancer researchers for decades, has been solved by scientists at the Cancer Research UK Beatson Institute and University of Glasgow. Generations of doctors and researchers have struggled to understand why a bowel...
by University of Edinburgh Receiver operating characteristic (ROC) curve analysis for the detection of colorectal cancer between cohorts. Area under the curve 0.85 (95% c.i. 0.80 to 0.90) for the single-fecal immunochemical test (FIT) cohort, 0.90 (0.87 to 0.93) for the first FIT analyzed (FIT1) of patients who completed at least one test and investigation in...
by University of Auckland Credit: CC0 Public Domain Old medicines, combined in new ways, are showing promise for treating bowel cancer, a group of University of Auckland researchers has found. “While there have been advances in treatments for this disease in recent years, the development of new medicines is expensive and time-consuming,” lead researcher Professor Peter Shepherd...
by University of Surrey Clinical audit of men and women diagnosed with CRC at St Mark’s Hospital: 2017–2020. Credit: Journal of Medical Screening (2022). DOI: 10.1177/09691413221100969 More than 70% of patients with bowel cancer are not diagnosed using official screening programs meaning diagnoses are often made late, when the cancer is at an advanced stage, according to...
ELIFE Scientists have shown how accelerated biological aging measured by an epigenetic clock may increase the risk of bowel cancer, according to a report published today in eLife. The study provides evidence that biological age might play a causal role in the increased risk of certain diseases, and paves the way for interventions that could...
EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY Lugano, Switzerland, 2 July 2021 – Doctors and patients are being advised to reduce unnecessary antibiotic use following new data suggesting that these medicines may increase the risk of cancer of the large intestine (colon), especially in people under 50 years. (1) The results, presented at the ESMO World Congress...
by Walter and Eliza Hall Institute Crypts and buds in the small intestine and colon. Credit: Dr. Maree Faux, WEHI. A biomarker in the blood of patients with bowel cancer may provide valuable insight into the risk of cancer relapse after surgery and the effectiveness of chemotherapy. Research published in PLOS Medicine found circulating tumor DNA...
by University of Glasgow Cancer cell during cell division. Credit: National Institutes of Health An international team of scientists have identified key factors underpinning the development of bowel or colorectal cancer in patients with a genetic predisposition to the disease. The study—led by researchers at the Cancer Research UK Beatson Institute at the University of Glasgow and the University of...
