by Lori Solomon Some patients seen in an inflammatory bowel disease (IBD) clinic screen positive for malnutrition, according to a research letter published online Nov. 20 in Gastro Hep Advances. Aaron C. Viser, from the University of North Carolina at Chapel Hill, and colleagues used data from a multidisciplinary IBD clinic (June 7 to July...
by UT Southwestern Medical Center Colonoscopic image of mice lacking the Pak2 gene showing severe colon inflammation. Credit: UT Southwestern Medical center A set of interacting molecules in immune cells of the gut is responsible for preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study. The findings,...
by American Physiological Society Credit: CC0 Public Domain The dietary supplement chlorophyllin alleviates inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, according to researchers from the Center for Diabetes and Metabolism Research at Sichuan University in China and from Cedars Sinai Medical Center in Los Angeles. In addition, chlorophyllin significantly reduces mortality related to...
Patients with inflammatory bowel disease (IBD) more often have spondyloarthritis (SpA) before and after diagnosis of IBD, according to a study recently published in the Journal of Crohn’s and Colitis. Sarita Shrestha, from Örebro University in Sweden, and colleagues compared the occurrence of SpA in a nationwide cohort study involving 39,203 patients diagnosed with IBD during 2006 to...
by Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public Domain Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai. The findings of two studies focused on this topic have been published in the journals IBD, of...
by Nicole Mlynaryk, University of California – San Diego The presence of Bacteroides vulgatus led to colitis in the mouse colon (left). However, protease inhibition protected the walls of the colon and reduced influx of inflammatory cells (right). Credit: University of California – San Diego Ulcerative colitis, a subtype of inflammatory bowel disease, is a...
by Karolinska Institutet Gastrointestinal System. Credit: Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. CC BY 3.0 Inflammatory bowel disease (IBD), with its two main disease entities Crohn’s disease and ulcerative colitis, is a chronic and relapsing inflammation of the gastrointestinal tract. The highest prevalence of...
The gut-infecting bacterium, Clostridioides difficile, commonly known as C. diff, sickens half a million people and causes up to 30,000 deaths in the United States each year. Often, C. difficile infection occurs after antibiotic treatment, which inadvertently kills members of the gut microbiota—the community of microbes living in our intestines—that normally bar C. difficile from invading the gut. However,...
by University of California – Riverside Dr. David Lo is a distinguished professor of biomedical sciences at UC Riverside. Credit: I. Pittalwala, UC Riverside. Biomedical scientists at the University of California, Riverside, propose a way for drugs to be more effective against inflammatory bowel disease, or IBD, in which the intestine undergoes inflammation. IBD, a...
Opioid receptors play key roles in regulating our senses and emotions. Recently, their discovery outside the nervous system raised several questions about the effects of opioids on the immune system. Now, researchers from Japan have shown that KNT-127—a drug that targets delta opioid receptors—can reduce pro-inflammatory signals in the colon. Their research highlights the immunomodulatory...
