September 10, 2024 by The North American Menopause Society Credit: Human Brain ProjectAs the median age of our population rises, so does the number of people diagnosed with Alzheimer’s disease. With advances in technology, it’s easier to determine brain age and identify blood-based Alzheimer’s disease biomarkers. A new study links trauma exposure with brain age...
— Alzheimer’s may be driven by multicellular communities, analysis suggests by Judy George, Deputy Managing Editor, MedPage TodaySeptember 3, 2024 Key TakeawaysTwo distinct pathways of brain aging emerged in a cellular analysis of post-mortem brain tissue.One trajectory led to Alzheimer’s disease, the other to an alternative brain aging pathway.Cellular communities, not singular cell subpopulations, may...
By Vijay Kumar MalesuReviewed by Lily Ramsey, LLM In a recent study published in npj Parkinson’s Disease, researchers explored how sex influences brain aging in Parkinson’s disease (PD) by analyzing Magnetic Resonance Imaging (MRI)-derived brain age differences and their clinical correlations. Study: Differences in brain aging between sexes in Parkinson’s disease. Image Credit: SpeedKingz/Shutterstock.comStudy: Differences...
by Buck Institute for Research on Aging mtd interacts with the retromer complex and is required for retromer maintenance. Credit: Nature Communications (2024). DOI: 10.1038/s41467-023-44343-3Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Buck Institute...
by Justin Jackson, Medical Xpress Machine Learning Indices, SPARE-AD and SPARE-BA, as a Function of Age. A, there was no significant difference observed between EDIC participants (blue) and controls without diabetes (orange). In panel B, EDIC participants showed a significant increase in predicted brain age (SPARE-BA) demonstrating more advanced brain aging patterns. SPARE-AD indicates spatial...
by CORDIS Correlation coefficients of predicted brain age and FreeSurfer features across control and schizophrenia (SZ) groups. Bivariate correlations are shown to provide an indication of the relative contribution of features in brain age prediction. The figure shows Pearson correlations between predicted brain age and cortical thickness features (top row), cortical surface areas (middle row)...
by Houston Methodist The interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for the very first viral entry into the human host. Some of the olfactory cells express ACE2 receptors that endocytose bound viral particles, before their way...
by University of Southern California Credit: CC0 Public Domain Researchers from a USC-led consortium have discovered 15 “hotspots” in the genome that either speed up brain aging or slow it down—a finding that could provide new drug targets to resist Alzheimer’s disease and other degenerative brain disorders, as well as developmental delays. The research appears...
Pauline Anderson Taking a daily multivitamin for 3 years is associated with a 60% slowing of cognitive aging, with the effects especially pronounced in patients with cardiovascular (CVD) disease, new research suggests. In addition to testing the effect of a daily multivitamin on cognition the COSMOS-Mind study also examined the effect of cocoa flavanols, but showed no...
Pauline Anderson November 11, 2021 Taking a daily multivitamin for 3 years is associated with a 60% slowing of cognitive aging, with the effects especially pronounced in patients with cardiovascular (CVD) disease, new research suggests. In addition to testing the effect of a daily multivitamin on cognition the COSMOS-Mind study also examined the effect of cocoa flavanols,...
