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‘Single-cell profiling’ shows how disease affects brain cell types and identifies potentially targetable pathways
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‘Single-cell profiling’ shows how disease affects brain cell types and identifies potentially targetable pathways

by Massachusetts Institute of Technology A figure from the paper depicts pathways perturbed in Alzheimer’s disease. Examples are listed for each pathway by major brain cell type. Credit: Tsai Lab/MIT Picower Institute After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But...