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Solving the dopamine riddle: New study pinpoints genetic mechanism linking brain chemical to schizophrenia

LIEBER INSTITUTE FOR BRAIN DEVELOPMENT Baltimore, Md. (November 1, 2022) – Researchers at the Lieber Institute for Brain Development(LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.    Through...

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Prescription drug improves symptoms of autism by targeting brain’s chemical messengers

UNIVERSITY OF CAMBRIDGE Bumetanide – a prescription drug for oedema (the build-up of fluid in the body) – improves some of the symptoms in young children with autism spectrum disorders and has no significant side effects, according to a new study from researchers in China and the UK. Published today in Translational Psychiatry, the study demonstrates for the first time that the drug improves the symptoms by decreasing the ratio...