By Rich Haridy April 03, 2022 The researchers found evidence of mild SARS-CoV-2 infections causing neuroinflammation, small bleeds in the brain and neuron damage Depositphotos A new study published in Nature Communications has offered the most comprehensive investigation to date into the effects of COVID-19 on the brain using nonhuman primates. The study found SARS-CoV-2 infection, regardless...
by National Institutes of Health Credit: Pixabay/CC0 Public Domain An anti-inflammatory drug candidate, known as 3,6′-dithiopomalidomide (DP) and designed by researchers at the National Institute on Aging (NIA), protected lab mice against cognitive decline by reducing brain inflammation. An international research team led by the NIA scientists has published their findings in Alzheimer’s and Dementia: The Journal...
by Anne Delotto Baier, University of South Florida David Lominadze, Ph.D., a professor of surgery and molecular pharmacology and physiology at the University of South Florida Health (USF Health) Morsani College of Medicine, investigates how microvascular changes induced by neuroinflammation may damage cognition, including short-term memory. Credit: USF Health/University of South Florida Neuroinflammatory diseases, including...
by Deutsches Zentrum fuer Diabetesforschung DZD Just where fat is deposited in the body and to what degree a person may benefit from a lifestyle intervention depends, among other things, on how sensitive the brain is to insulin. If the person’s brain responds sensitively to the hormone, a significant amount of weight can be lost,...
University of Kentucky UNIVERSITY OF KENTUCKY LEXINGTON, Ky. (April 9, 2020) — Linda J. Van Eldik, director of the Sanders-Brown Center on Aging at the University of Kentucky, co-authored a paper reporting the first human clinical study of a drug candidate that suppresses injury and disease-induced inflammation of the brain. The paper was accepted in...
By Osman Shabir, M.Sc. Reviewed by Dr. Jennifer Logan, MD, MPH Fibromyalgia is a condition in which there is extensive chronic pain across the body with an increased pain response to pressure, which would normally not be painful. Central to the pathogenesis of fibromyalgia is impaired nociceptive (pain) signal processing in the nervous system. Therefore, fibromyalgia in its pure form is...
By Tim Newman Fact checked by Gianna D’Emilio In this Spotlight, we introduce the glymphatic system: the brain’s dedicated waste clearance system. Now implicated in various conditions, it is high time that we became acquainted. Many of us are relatively familiar with the lymphatic system; it performs a number of roles, one of which is...
New research conducted at the Lady Davis Institute (LDI) at the Jewish General Hospital reveals that a novel drug reverses memory deficits and stops Alzheimer disease pathology (AD) in an animal model. Importantly, this drug has already proven to be non-toxic for humans in a clinical setting and could, therefore, be brought quickly to trials...
Surprising finding fills gap in understanding astrocytes’ role in brain disease SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Astrocytes–the star-shaped cells of our brain–are very busy. Their job description includes maintaining the blood-brain barrier, removing excess neurotransmitters, repairing brain tissue and more. IMAGE: THIS IS JEROLD CHUN, M.D., PH.D., PROFESSOR AND SENIOR VICE PRESIDENT OF NEUROSCIENCE...
UNIVERSITY OF ILLINOIS COLLEGE OF AGRICULTURAL, CONSUMER AND ENVIRONMENTAL SCIENCES URBANA, Ill. – As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function. That’s one explanation for why memory fades and other brain functions decline during old age....
