Tag: <span>brain metastasis</span>

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Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation
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Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

by Tel-Aviv University Brain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/- mice injected intracardially with BT-EO771 cells, (WT n = 10, Lcn2-/- n = 9 mice) (Kaplan–Meier curve, log-rank test). c. Quantification of brain metastatic burden for mice in (a), quantified as %...

AI better than human eye at predicting brain metastasis outcomes, find researchers
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AI better than human eye at predicting brain metastasis outcomes, find researchers

by York University Architecture of (a) vanilla 3D residual network (baseline), (b) the 3D residual network with CBAM attention, (c) the proposed self-attention-guided 3D residual network, (d) the residual block in 3D residual network, consisting of residual connections, (e) the CBAM attention block consisting of the channel and spatial attention modules, and (f) the self-attention...

Warning: Popular Vitamin Supplement Causes Cancer Risk and Brain Metastasis
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Warning: Popular Vitamin Supplement Causes Cancer Risk and Brain Metastasis

By UNIVERSITY OF MISSOURI-COLUMBIA NOVEMBER 12, 2022 New research finds that the popular dietary supplement nicotinamide riboside could increase the risk of serious disease, including developing cancer. University of Missouri researchers made the discovery while using bioluminescent imaging technology to study how nicotinamide riboside supplements work inside the body. Commercial dietary supplements like nicotinamide riboside (NR), a...

Novel brain-permeable BRAF inhibitor shows promise in more effectively reaching and treating melanoma brain metastasis
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Novel brain-permeable BRAF inhibitor shows promise in more effectively reaching and treating melanoma brain metastasis

VALL D’HEBRON INSTITUTE OF ONCOLOGY IMAGE: JOAN SEOANE, CO-DIRECTOR OF PRECLINICAL AND TRANSLATIONAL RESEARCH AT THE VALL D’HEBRON INSTITUTE OF ONCOLOGY (VHIO). CREDIT: VALL D’HEBRON INSTITUTE OF ONCOLOGY (VHIO). Published in Cancer Research, findings reveal the potent and prolonged antitumor activity of C1a in patient-derived preclinical models of mutant-BRAF-driven melanoma brain metastases, even upon relapse on...