by Massachusetts General Hospital ICB increases GBM vascular leakage and induces brain edema. MR T2-weighted-Fluid-Attenuated Inversion Recovery (T2-FLAIR) images obtained from a recurrent GBM patient (A) before and (B) after 4 mo of anti-PD-L1 (MEDI4763; NCT02336165) treatment show increased edema after ICB treatment. In addition to ICB-induced inflammation, this change may be due in part...
By Rich Haridy November 23, 2021 Aducanumab was controversially approved by the FDA in June despite an advisory panel recommending against its approvalracorn/Depositphotos A new study published in the journal JAMA Neurology is reporting more than one in three patients trialing the recently approved Alzheimer’s drug aducanumab experienced brain swelling side effects. The data is the first...
by Jennifer Michalowski, University of Utah Health Sciences Credit: CC0 Public Domain Following a brain-injuring bump or blow to the head, brain cells and blood vessels typically swell. This can lead to a potentially life-threatening increase in pressure inside the skull, and managing swelling is critical for patients with traumatic brain injuries (TBIs). But researchers at...
by Jennifer Michalowski, University of Utah Health Sciences Following a brain-injuring bump or blow to the head, brain cells and blood vessels typically swell. This can lead to a potentially life-threatening increase in pressure inside the skull, and managing swelling is critical for patients with traumatic brain injuries (TBIs). But researchers at University of Utah Health...
The groin is the area of the pelvis where the genitals are located. It extends up from there to the hip. There are many potential causes of a lump in this area. Some are relatively benign, while others can be much more serious. The groin contains numerous muscles, ligaments, blood vessels, and nerves. As a...
We are all familiar with the drawbacks of dehydration, but we rarely hear about the harmful effects of overhydration. For one, excess fluid accumulation can lead to dangerously low sodium levels in the blood or hyponatremia—a life-threatening condition that can result in brain swelling. Similarly, more is known about the mechanisms in the body that...
