by Tel-Aviv University αEGFR-SOX2-LNP mediates therapeutic gene editing in a xenograft HNSCC mouse model. Credit: Advanced Science (2024). DOI: 10.1002/advs.202411032 Researchers from Tel Aviv University utilized CRISPR to cut a single gene from cancer cells of head and neck tumors—and successfully eliminated 50% of the tumors in model animals. This study was led by Dr. Razan Masarwy, MD,...
Tag: <span>brain tumor</span>
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Research discovery halts childhood brain tumour before it forms
Posted on February 4, 2025 Summary: A SickKids research team has identified a critical event driving tumour growth in a type of medulloblastoma – and a way to block it. Scientists at The Hospital for Sick Children (SickKids) have discovered a way to stop tumour growth before it starts for a subtype of medulloblastoma, the most...
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Tumor-secreted protein may hold the key to better treatments for deadly brain tumor
by University of California, Los Angeles Schematic summary illustrating the role of Endocan in GBM-VE crosstalk. Credit: Nature Communications (2025). DOI: 10.1038/s41467-024-55487-1 A study co-led by UCLA scientists has found targeting a protein called endocan and its related signaling pathway could be a promising new approach for treating glioblastoma, an aggressive and lethal type of brain cancer. The...
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Molecular zip code draws killer T cells straight to brain tumors
Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice. The technology will soon be tested in a clinical trial for people with glioblastoma.Peer-Reviewed Publication University of California – San Francisco More information, including a copy of the paper, can be found online at...
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Breakthrough Therapy Obliterates Deadly Brain Tumor in Days
ByMIKE MCRAE MRI scan of 72-year-old glioblastoma patient. (Choi et al., NEMJ, 2024)Brain scans of a 72-year-old man diagnosed with a highly aggressive form of cancer known as a glioblastoma have revealed a remarkable regression in his tumor’s size within days of receiving an infusion of an innovative new treatment. Though the outcomes of two...
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Oral Drug for Brain Tumor Could Change Treatment Landscape
Neil Osterweil June 04, 2023 UPDATED June 9, 2023 // Editor’s note: This story has been updated with additional comments from Dr Rimas Vincas Lukas of Northwestern University. CHICAGO — Patients with a certain type of brain tumor could soon be treated with an oral targeted drug instead of undergoing more toxic chemotherapy and radiation, say researchers reporting new results...
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Oral Drug for Brain Tumor Could Change Treatment Landscape
Neil Osterweil June 04, 2023 CHICAGO — Patients with a certain type of brain tumor could soon be treated with an oral targeted drug instead of undergoing more toxic chemotherapy and radiation, say researchers reporting new results that could potentially change the treatment landscape. The investigational drug vorasidenib (Servier) is awaiting approval for use in gliomas bearing...
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Revolutionary Brain Tumor Treatment Discovered in Traditional Chinese Medicine
By BROWN UNIVERSITY APRIL 18, 2023 A new study has revealed the potential of a drug derived from indirubin, a natural compound used in traditional Chinese medicine, in treating malignant brain tumors in mice. Published in Cell Reports Medicine, the research highlights how a formulation of indirubin improved mice’s survival rates and moved the drug closer to clinical...
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Brain tumor discovery paves way for new drug treatments
UNIVERSITY OF NOTTINGHAM New research has shown that the blood vessels that feed aggressive brain tumours have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumours of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves. Scientists from...
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New method eradicates deadly brain tumors by ‘starving’ them of energy source
by Tel Aviv University Dr. Lior Mayo and students. Credit: Tel Aviv University A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and...