by Katie Paradis, Children’s Hospital Boston Graphical abstract. Credit: Brain Research (2021). DOI: 10.1016/j.brainres.2021.147348 Researchers from the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center recently found that levels of a specific protein detected through a patient’s urine can track a tumor’s size and responsiveness to treatment in children with diffuse intrinsic pontine gliomas (DIPG). This discovery helps steer the course...
by Max Delbrück Center for Molecular Medicine Previously only suspected, now made it visible thanks to the molecular reporter: where human tumor cells and brain cells of a mouse meet, the tumor cells have a different identity than everywhere else (green). Credit: Gargiulo Lab, MDC Glioblastoma is the most common malignant brain tumor in adults. Roughly...
by Dorian Martin, Texas A&M University A team led by Texas A&M University’s College of Veterinary Medicine & Biomedical Sciences’ (CVM) researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer. The Texas A&M team’s research focuses on the AH...
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center In a first-of-its kind study, neurologists at Beth Israel Deaconess Medical Center (BIDMC) tested the use of non-invasive electrical stimulation as a novel therapeutic approach to brain tumors. In an experiment published in Science Advances, the scientists—led by Emiliano Santarnecchi, Ph.D., principal investigator at the Berenson-Allen Center...
Investigators were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a Northwestern Medicine study published in Cell Reports. Glioblastoma cells (orange) spread throughout a fly brain (normal cells in blue), used to model human cancer. Credit: Northwestern University The discovery of this enzyme’s...
New research brings fresh hope of a new treatment for patients with glioblastoma, after identifying a way to halt the growth of this life-threatening brain tumor. Researchers may have found a way to halt the growth of deadly glioblastoma brain tumors. Scientists from the Massachusetts Institute of Technology (MIT) in Boston have identified the mechanism by...
New technique developed at Washington University in St. Louis uses blood test Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test. IMAGE: A TEAM OF ENGINEERS...
Glioblastoma brain tumors are notoriously difficult to treat, and the prognosis is poor for people with this type of brain cancer. However, a new study may have discovered a way to halt glioblastoma growth and increase patient survival. Blocking a protein called TRF1 could halt the growth of glioblastomas, say researchers. By inhibiting a...
