by University of Minnesota In the story of Goldilocks, a little girl tastes three different bowls of porridge to find which is not too hot, not too cold, but just the right temperature. In a study published in Advanced Therapeutics, University of Minnesota Medical School researchers report on a “Goldilocks” balance which holds the key to awakening...
Tag: <span>Brain tumors</span>
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Medicare patients with multiple sclerosis bear the burden of rising drug prices
by University of Pittsburgh Over the course of a decade, out-of-pocket costs for multiple sclerosis drugs rose more than sevenfold for Medicare Part D beneficiaries, according to a JAMA Neurology study published today by researchers at the University of Pittsburgh. Using Medicare claims data from 2006-2016, the researchers looked at trends in multiple sclerosis drug...
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Exercise and antioxidants: A winning combination for brain health?
by Matt Miles , Medical Xpress An international team of researchers representing several institutions in Japan and the US has published promising findings that may stand to benefit people living with the specter of Alzheimer’s and other neurodegenerative diseases, as well as age-related cognitive decline. In their paper published in PNAS, “Leptin in hippocampus mediates benefits...
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Why some brain tumors respond to immunotherapy
NEW YORK, NY (February 15, 2019)– Columbia researchers have learned why some glioblastomas–the most common type of brain cancer–respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly effective treatments. The study, led by Raul Rabadan, PhD,...
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When it comes to brain tumors, a patient’s sex matters
Have you ever wondered why, in most species, males are larger and more ornamented than females? It’s an evolutionarily determined aspect of biology, but what does it mean for human health and disease? What are the implications of needing one chart to describe normal growth in boys, and another to describe normal growth in girls?...
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Some brain tumors may respond to Immunotherapy, new study suggests
Immunotherapy has proved effective in treating a number of cancers, but brain tumors have remained stubbornly resistant. Now, a new study suggests that a slow-growing brain tumor arising in patients affected by neurofibromatosis type 1 (NF1) may be vulnerable to Immunotherapy, which gives the immune system a boost in fighting cancer. The findings, made by an international consortium led by researchers at Columbia University Vagelos College of...
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Team finds missing immune cells that could fight lethal brain tumors
Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients in the bone marrow, locked away and unable to function because of a...
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Study finds mutation driving deadlier brain tumors and potential therapy to stop it
July 9, 2018, Perelman School of Medicine at the University of Pennsylvania A poorly understood mutation in the brain cancer glioblastoma (GBM) is now being implicated for the first time as the driver of rare but deadlier cases of the disease, a team of researchers from the Perelman School of Medicine at the University of Pennsylvania and the...
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Molecules that could help to prevent the development of brain tumors
Researchers from the University of Portsmouth’s Brain Tumour Research Centre of Excellence have identified molecules which are responsible for metastatic lung cancer cells binding to blood vessels in the brain. In order for a cancer cell to enter the brain, it must first bind to the cells which line the structure separating the blood from...
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Radiation therapy vital to treating brain tumors, but it exacts a toll
Radiation therapy (RT) using high-energy particles, like x-rays or electron beams, is a common and critical component in successfully treating patients with brain tumors, but it is also associated with significant adverse effects, such as neuronal loss in adjacent healthy tissues. In a new study, published in the June issue of Brain Connectivity, researchers at the...