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Putting the brakes on immune reactions
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Putting the brakes on immune reactions

by  Rockefeller University The flurry of activity between B cells (blue), T cells (red), and T cells expressing Foxp3 (green), as a germinal center collapses. Credit: Johanne Jacobsen When we are exposed to a pathogen, the immune system’s B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot...

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Tampering with the Brakes

We’ve all seen these people. Maybe at one point in time we’ve actually been these people: messy, falling-down drunk, slurring and incoherent, precariously close to catastrophe … and asking the bartender for another shot. For the majority of us who imbibe, there is a certain point at which we stop pounding the drinks, and many...