In a line of dominos, if you take out a single piece, the last one will never fall. Similarly, a lot of pieces have to line up and be pushed at the same time in a cell to result in cancer. Twenty-two years ago, Cold Spring Harbor Laboratory (CSHL) Professor Alea Mills discovered the protein p63. More...
Tag: <span>Breaking chain</span>
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Breaking the chain that culminates in cancer
COLD SPRING HARBOR LABORATORY IMAGE: SQUAMOUS CELLS MAKE UP THE OUTER LAYER OF SEVERAL ORGANS, SUCH AS SKIN, TONGUE, AND ESOPHAGUS. THIS IMAGE SHOWS A TUMOR FROM A PATIENT WITH SQUAMOUS CELL CARCINOMA. THE CANCER CELLS OVERPRODUCE A CANCER-CAUSING VERSION OF THE PROTEIN P63, CALLED ∆NP63Α (STAINED BROWN IN THIS IMAGE). HIGH LEVELS OF ∆NP63Α...