Graphic representation of the functional role of DAPK3 in TNBC cells. Credit: PNAS Nexus (2024). DOI: 10.1093/pnasnexus/pgae401 Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone. They experience worse outcomes than patients with other...
Tag: <span>Breast Cancer</span>
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Study confirms fibrosis as a prognostic indicator in the most common breast cancer
September 19, 2024 by The Spanish National Cancer Research Centre Histological slide of cancerous breast tissue. The pink “riverways” are normal connective tissue, and the blue is cancer cells. Credit: Cecil Fox, National Cancer Institute (NIH).The most common breast cancer is HER2-negative, so called because it has low amounts of one of the proteins that...
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Breast cancer rises among Asian American and Pacific Islander women
September 9, 2024 by Phillip Reese, KFF Health News Credit: Pixabay/CC0 Public DomainAbout 11,000 Asian American and Pacific Islander women were diagnosed with breast cancer in 2021 and about 1,500 died. The latest federal data shows the rate of new breast cancer diagnoses in Asian American and Pacific Islander women—a group that once had relatively...
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Fewer than 3 of 10 women cite diet when asked how to reduce chances of breast cancer
News Release 26-Aug-2024 Nationwide survey preceding breast cancer awareness month also shows lack of knowledge of protective benefits of soy and harmful effects of dairy Reports and ProceedingsPhysicians Committee for Responsible Medicine WASHINGTON, D.C. ؚ— Just 28% of U.S. women are aware that a healthful diet can lower the risk of developing breast cancer, according...
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Team discovers role of ferroptosis in combating breast cancer resistance
September 13, 2024 by Jeni Bushman, University of Illinois at Urbana-Champaign Transmission electron microscopy (TEM) analyses to monitor cell morphology and mitochondrial integrity. Credit: Breast Cancer Research and Treatment (2024). DOI: 10.1007/s10549-024-07420-9An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer. Their findings, published...
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Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer
September 13, 2024 by Dana-Farber Cancer Institute A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial led by Dana-Farber Cancer Institute researchers, reinforce earlier...
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Scientists identify potential new immune system target to head off the spread of breast cancer cells
September 3, 2024 by Johns Hopkins University School of Medicine In a sea of cancer cells (blue), macrophages (green) are close neighbors to metastatic-initiating cancer cells (magenta). Credit: Won Jin Ho, Johns Hopkins Kimmel Cancer CenterIn a study using human breast cancer cells, scientists say they have potentially identified immune system white blood cells that...
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miR-10b Inhibition: A strategy for treating metastatic breast cancer
News Release 28-Aug-2024 “We have developed a nanodrug, termed MN-anti-miR10b, that delivers anti-miR-10b antisense oligomers to cancer cells.” Peer-Reviewed PublicationImpact Journals LLC image: Figure 5: miR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubation with Aldefluor reagent. (B) Fluorescence microscopy of representative MCF-7 cells...
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Drug shows promise for treating brain tumors resulting from breast cancer, trial reports
August 8, 2024 by Steven Lee, University of Texas Health Science Center at San Antonio Sacituzumab govitecan (SG) inhibits tumor growth in a xenograft model of intracranial breast cancer. Representative bioluminescent images of control and sacituzumab govitecan treated (25 mg/kg/twice weekly) mice at the start of treatment (top panels) and 2 weeks after treatment (bottom panels)....
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AI system diagnoses breast cancer with near 100% accuracy
JUNE 25, 2024 by Cesareo Contreras, Northeastern University Microscopy images demonstrating the four classes in the BACH dataset. Credit: Cancers (2024). DOI: 10.3390/cancers16122222Earlier this year, Northeastern University researchers unveiled a web-based artificial intelligence tool designed to diagnose prostate cancer at a faster and more accurate rate. Now, the same group, led by bioengineering professor Saeed...