by National University of Singapore A working model for integrin αvβ1 in the tumor microenvironment. Credit: Journal of Extracellular Vesicles One woman is diagnosed with breast cancer every 14 seconds somewhere around the globe—based on data showing that an approximate 2.3 million women worldwide were newly diagnosed with breast cancer in 2020. In Singapore, it is...
by Garvan Institute of Medical Research Collagen fibers running through a cancer tumor, created using a multiphoton microscope. The coloring is a visual representation of how collagen fibers are organized. Changing levels of collagen XII alters this organization; increasing collagen XII produces collagen fibers that are thicker and more aligned. Credit: Matrix and Metastasis Lab,...
TUFTS UNIVERSITY IMAGE: BREAST TUMOR CELLS WITH A DYE THAT INDICATES THE ELECTRICAL POTENTIAL OF THE CELLS. CREDIT: MADELEINE OUDIN, TUFTS UNIVERSITY In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens. Marked by a breakdown in the normal electrical patterns generated by the cells, they lose...
by Cold Spring Harbor Laboratory Certain regulatory RNAs are involved in cancer cell movement and metastases. On the right, cancer cells are on the move with long, stiff actin filaments (in green) acting like fingers to help it move. Paxillin (red) collects in patches on the cell’s edge, sticking it to a surface. On the left,...
UNIVERSITY OF KENTUCKY LEXINGTON, Ky. (Feb. 5, 2020) – A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis. Metastasis is when cancer cells spread from the primary tumor to surrounding tissues and distant...
