A breast cancer cell is like a house with three locks on the front door. Keys, or receptors, allow drugs to unlock the door and kill the cell. However, in triple-negative breast cancer, these keys are absent, thereby resulting in few options for drug therapy, until now. A protein called p53 suppresses and kills cancer in people. However, a defective, mutant form of...
Tag: <span>Breast Cancer</span>
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Amino Acid Leucine Found In Meat May Fuel Resistance To Breast Cancer Treatment Tamoxifen
By Rubi Valdez Tech Times Breast cancer patients who are resistant to the drug tamoxifen have poor health outcomes, but reducing meat protein in the diet could offer better results. Tamoxifen is the standard treatment for estrogen-receptor-positive breast cancer. Many tumors became resistant to this endocrine drug that treating breast cancer becomes more difficult due to limited treatment options. A group of researchers from the Cancer Center...
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Researchers report a new targetable vulnerability in breast cancer cells
by University of Helsinki New study reveals that FGFR4 phosphorylates the essential proteins (MST1/2) of Hippo tumor suppressor pathway preventing their activation and induction of programmed cell death in breast cancer cells. Cell death program can be reactivated by blocking FGFR4 function with a speficic inhibitor. These findings suggest new options for eradicating cancer cells...
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Hope for two million cancer patients: New Immunotherapy is the first to shrink lung, breast and mesothelioma tumors
Immunotherapy is the most cutting edge treatment in cancer therapies The treatment reprograms patient’s immune cells to attack cancer cells So far, one of the leading forms is CAR T therapy, but it only works against blood cancers like non-Hodkins lymphoma But in a world-first, Memorial Sloan Kettering scientists have developed a version of CAR T therapy that can treat...
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New findings indicate additional benefits of exercise to breast cancer survivors
Can exercise reduce the risk of heart disease in women with breast cancer? That’s what Kyuwan Lee Ph.D. ’19 investigated as a part of study led by Christina Dieli-Conwright, “Effects of Aerobic and Resistance Exercise on Metabolic Syndrome, Sarcopenic Obesity, and Circulating Biomarkers in Overweight or Obese Survivors of Breast Cancer: A Randomized Controlled Trial.” Their findings, published in the Journal of the American Medical Association, Oncology,...
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Time-restricted eating may prove to be a dietary intervention against breast cancer
Reviewed by Alina Shrourou, BSc Changing when you eat rather than what you eat may prove to be a dietary intervention against breast cancer, suggests a new mouse study to be presented Saturday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La. A growing body of evidence indicates that obesity and metabolic syndrome–a...
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Scientists tie walnuts to gene expressions related to breast cancer
MARSHALL UNIVERSITY JOAN C. EDWARDS SCHOOL OF MEDICINE HUNTINGTON, W.Va. – New research from Marshall University links walnut consumption as a contributing factor that could suppress growth and survival of breast cancers. Led by W. Elaine Hardman, Ph.D., a professor in the Department of Biomedical Sciences at the Marshall University Joan C. Edwards School of...
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FDA approves first Immunotherapy drug for breast cancer
The combination of immunotherapy (Tecentriq) and chemotherapy (Abraxane) was given accelerated approval for triple-negative breast cancer that is locally advanced or has metastasized, cannot be surgically removed, and is programmed death-ligand 1-postive, CNNreported. A study published last October in the New England Journal of Medicine revealed a median progression-free survival of 7.4 months among patients...
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New gene hunt reveals potential breast cancer treatment target
Australian and US researchers have developed a way to discover elusive cancer-promoting genes, and have already identified one that appears to promote aggressive breast cancers. The University of Queensland and Albert Einstein College of Medicine team has developed a statistical approach to reveal many previously hard-to-find genes that contribute to cancer. Associate Professor Jess Mar, of UQ’s...
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New cell-tracking technique sheds light on breast cancer spread
By Catharine Paddock PhD Fact checked by Jasmin Collier A leading-edge genetic technique that can track cell lineage has revealed much about how breast cancer spreads. It could also help explain why some breast cancers relapse after initially successful chemotherapy. The name of the technique is cellular barcoding, and it allows scientists to assess the...