Chemists at Hong Kong Baptist University (HKBU) have discovered the use of a metal compound that inhibits the enzyme closely associated with triple-negative breast cancer (TNBC), one of the most difficult forms of breast cancer to treat. The metal compound is found to inhibit the TNBC tumors with less toxicity in mice, thus their work...
Tag: <span>Breast Cancer</span>
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Cancer cells are weaker when made more acidic
Cancer cells function less well and are less able to multiply when their internal environment is made more acidic. Making cancer cells more acidic could quell their ability to multiply. This was the conclusion that researchers in the United States and Spain came to after they used a computer model to study the conditions that affect metabolic...
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Breast cancer diagnosed by pill
Scientists have developed a pill that lights up breast cancer tumors. Approximately one in three breast cancer patients undergo unnecessary surgery or chemotherapy on tumors that are benign. There are also women with treatable cancers who die due to undetected tumors that are hidden by dense breast tissue. This is due to difficulties inherent in...
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Glue-like protein may be key to drug-resistant breast cancer
Scientists have found it challenging to understand why some breast cancers become resistant to drugs. A recent study concludes that a sticky protein might be the answer. A glue-like protein may help to explain breast cancer drug resistance. The hormone estrogen plays a vital part in the development of breast cancer. An estimated 70 percent of all breast cancers are...
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Woman’s late-stage breast cancer cured by immunotherapy treatment that supercharged her own cells to fight the disease in a world first
Immunotherapy enhances a patient’s own T cells to make them fight cancer better Doctors at the National Institutes of Health have cured a woman of her breast cancer using the experimental new treatment A woman has been cured of her breast cancer by a revolutionary treatment that used supercharged versions of her own immunity cells...
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Landmark study finds more breast cancer patients can safely forgo chemotherapy
Loyola Medicine oncologist Kathy Albain, M.D., is among main co-authors of New England Journal of Medicine study LOYOLA UNIVERSITY HEALTH SYSTEM MAYWOOD, IL – A 21-gene test performed on tumors could enable most patients with the most common type of early breast cancer to safely forgo chemotherapy, according to a landmark study published in the New...
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Particle shows promise for treating the deadliest type of breast cancer
Like a smart bomb, the potential treatment targets a cancer-enabling agent to prevent lung metastasis USC researchers have pinpointed a remedy to thwart a protein that helps the metastatic spread of breast cancer, a leading cause of death for women. The findings appear today in Nature Communications. IMAGE: METASTATIC BREAST CANCER CELLS (YELLOW) INTERACTING WITH MACROPHAGES (MAGENTA). The study...
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New ‘Pan-Cancer’ analysis reveals the common roots of different cancers
In the largest study of its kind, cancer researchers analyzed and classified over 10,000 tumors from 33 cancer types to trace connections between different cancers. Typically cancers are classified by where they originate in the body–think breast cancer, stomach cancer, and so on. But a collaboration called the Pan-Cancer Initiative, launched in 2012 at a...
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Answers to 100-year-old mystery point to potential breast cancer therapies
New insights into how cancer cells fuel their growth are opening novel possibilities for cancer treatment. A team of researchers at Baylor College of Medicine and Roswell Park Comprehensive Cancer Center has identified a long sought after the connection between how cancer cells use the sugar glucose to generate energy – the Warburg pathway –...
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Researchers identify compound to prevent breast cancer cells from activating in brain
Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain. The Houston Methodist researchers culled through thousands of existing drugs to see if they could identify a compound that would prevent cancer cells from spreading, or...