by Harvard Medical School Credit: Pixabay/CC0 Public Domain In what may turn out to be a long-missing piece in the puzzle of breast cancer, Harvard Medical School researchers have identified the molecular sparkplug that ignites cases of the disease currently unexplained by the classical model of breast-cancer development. A report on the team’s work is published...
by Wiley Credit: Unsplash/CC0 Public Domain In a recent study, having depression before or after a breast cancer diagnosis was associated with a lower likelihood of survival. The findings are published in the journal Cancer. For the study, Bin Huang, DrPH, of the University of Kentucky Markey Cancer Center, and his colleagues analyzed data from the Kentucky Cancer Registry...
by Krista Conger, Stanford University Medical Center Landmarking analysis to evaluate the impact of antimicrobial exposure on survival over time on N = 772 independent patients. Data were presented as the hazard ratios ± 95% confidence intervals that reflect the risk of ongoing antimicrobial exposure at yearly intervals post-diagnosis and are plotted for the cumulative exposure definitions of total and...
UNIVERSITY OF BASEL Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medication. This is the case, for example, with alpelisib, a drug that has been approved for use in Switzerland for the past few years as a treatment for advanced breast...
by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain A paper published in the American Journal of Human Genetics proposes ATRIP gene variants as a breast cancer susceptibility gene candidate based on a study of women without any of the known breast cancer-associated gene variants. The team of Canadian and Polish researchers led by the University of Toronto...
There is a relative increase of around 20% to 30% in breast cancer risk associated with current or recent use of either combined oral or progestagen-only contraceptives.” By Amanda Prestigiacomo Mar 25, 2023 Peter Dezeley via Getty Images Hormonal contraceptives come with an increased risk of breast cancer, according to a new study conducted by...
by Leibniz Research Centre for Working Environments and Human Factors in Dortmund EDI3 expression and enzyme activity according to HER2 and ER status. A, EDI3 (GPCPD1; 224826_at) mRNA expression was compared among subtypes defined according to HER2 and ER status in human breast cancer Affymetrix datasets (total n = 540). B, EDI3 protein expression in breast cancer subtypes using...
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: RESEARCH IMAGE CREDIT: POSTECH Breast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major cancers, it is the only one that has shown an increasing trend over the past 20 years. The chance of survival would be higher if breast...
by Medical College of Wisconsin PD-L2 immunostaining in ER+ breast cancer. (A-C; brown signal) Immunohistochemistry of PD-L2 using diaminobenzidine chromogen and (D-F; red signal) immunofluorescence. A, B, D, and E are different examples of ER+ tumors with high cancer cell expression of PD-L2, whereas C and F are examples with low cancer cell PD-L2 expression....
Reviewed by Emily Henderson, B.Sc. Jan 17 2023 An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory system, and form new, metastatic tumors in other parts of the...
