BAR-ILAN UNIVERSITY IMAGE: CANCER CELLS USE FEET-LIKE PROTRUSIONS CALLED INVADOPODIA TO DEGRADE UNDERLYING TISSUE, ENTER THE BLOODSTREAM AND FORM METASTASES IN OTHER ORGANS. APPROXIMATELY FOUR YEARS AGO DR. HAVA GIL-HENN AND RESEARCHERS FROM THE AZRIELI FACULTY OF MEDICINE OF BAR-ILAN UNIVERSITY REVEALED TWO IMPORTANT CLUES ABOUT THE FORMATION OF INVADOPODIA: THE CELLULAR LEVEL OF THE...
7 September 2022 IMAGE SOURCE, JAMES DYSON AWARD By Shiona McCallumTechnology reporter A device to help detect breast cancer has won the prestigious UK James Dyson Award. The Dotplot aims to help women self-check at home and track any changes they may find on an app. Breast cancer is the second most common cause of...
by The Spanish National Cancer Research Centre Clinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm. A Clinical trial treatment and sampling schedule. After randomization, patients were scheduled for a fresh tumor biopsy. Sixty-two and sixty-one patients allocated to the Experimental and Standard arms, respectively, consented to and underwent...
by University of Glasgow Graphical abstract. Credit: Journal of Experimental Medicine (2022). DOI: 10.1084/jem.20211431 Breast cancer immunotherapy could be more effective if an immune cell that prevents it from working is targeted at the same time, according to new research from the University of Glasgow. This discovery, published in the Journal of Experimental Medicine, may be the first...
by University of California, Los Angeles Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Karen Meaburn, Ph.D. at the NIH IRP. A UCLA Jonsson Comprehensive Cancer Center researcher and collaborators in a multicenter...
by Edith Cowan University Credit: Pixabay/CC0 Public Domain Breast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer by the age of 85. Radiotherapy has emerged as an important component of breast cancer treatment but can lead to cancer-related fatigue and negatively impact...
by Hokkaido University In IL-34-expressing tumors, blood vessels were observed only in the outer layer, whereas in IL-34-deficient tumors, blood vessels were observed in the whole area (modified from Nabeel Kajihara, et al. Cancer Immunology, Immunotherapy. September 14, 2022) Credit: Nabeel Kajihara, et al. Cancer Immunology, Immunotherapy. September 14, 2022 Triple-negative breast cancer (TNBC) tumors...
by Mikayla Mace Kelley, University of Arizona cSNX1.3 competitively inhibits binding of EGFR to SNX1. A Ribbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZS). The proposed SNX1 binding site is well away from the kinase active site. B SDS page gels for purified SNX1 Bar domain (residues 301–522) and EGFR kinase...
by Blake Belden, Virginia Commonwealth University Credit: Unsplash/CC0 Public Domain Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options. Breast cancer is the second most common cancer in U.S. women, and triple-negative breast cancer(TNBC) is a more aggressive and...
Reviewed by Emily Henderson, B.Sc. Oct 17 2022 Research led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans’ Schools of Medicine and Graduate Studies, reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug suppresses the growth of triple-negative breast cancer cells synergistically. The findings are published...
