by Leibniz Research Centre for Working Environments and Human Factors in Dortmund EDI3 expression and enzyme activity according to HER2 and ER status. A, EDI3 (GPCPD1; 224826_at) mRNA expression was compared among subtypes defined according to HER2 and ER status in human breast cancer Affymetrix datasets (total n = 540). B, EDI3 protein expression in breast cancer subtypes using...
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: RESEARCH IMAGE CREDIT: POSTECH Breast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major cancers, it is the only one that has shown an increasing trend over the past 20 years. The chance of survival would be higher if breast...
by Medical College of Wisconsin PD-L2 immunostaining in ER+ breast cancer. (A-C; brown signal) Immunohistochemistry of PD-L2 using diaminobenzidine chromogen and (D-F; red signal) immunofluorescence. A, B, D, and E are different examples of ER+ tumors with high cancer cell expression of PD-L2, whereas C and F are examples with low cancer cell PD-L2 expression....
Reviewed by Emily Henderson, B.Sc. Jan 17 2023 An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory system, and form new, metastatic tumors in other parts of the...
BAR-ILAN UNIVERSITY IMAGE: CANCER CELLS USE FEET-LIKE PROTRUSIONS CALLED INVADOPODIA TO DEGRADE UNDERLYING TISSUE, ENTER THE BLOODSTREAM AND FORM METASTASES IN OTHER ORGANS. APPROXIMATELY FOUR YEARS AGO DR. HAVA GIL-HENN AND RESEARCHERS FROM THE AZRIELI FACULTY OF MEDICINE OF BAR-ILAN UNIVERSITY REVEALED TWO IMPORTANT CLUES ABOUT THE FORMATION OF INVADOPODIA: THE CELLULAR LEVEL OF THE...
7 September 2022 IMAGE SOURCE, JAMES DYSON AWARD By Shiona McCallumTechnology reporter A device to help detect breast cancer has won the prestigious UK James Dyson Award. The Dotplot aims to help women self-check at home and track any changes they may find on an app. Breast cancer is the second most common cause of...
by The Spanish National Cancer Research Centre Clinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm. A Clinical trial treatment and sampling schedule. After randomization, patients were scheduled for a fresh tumor biopsy. Sixty-two and sixty-one patients allocated to the Experimental and Standard arms, respectively, consented to and underwent...
by University of Glasgow Graphical abstract. Credit: Journal of Experimental Medicine (2022). DOI: 10.1084/jem.20211431 Breast cancer immunotherapy could be more effective if an immune cell that prevents it from working is targeted at the same time, according to new research from the University of Glasgow. This discovery, published in the Journal of Experimental Medicine, may be the first...
by University of California, Los Angeles Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Karen Meaburn, Ph.D. at the NIH IRP. A UCLA Jonsson Comprehensive Cancer Center researcher and collaborators in a multicenter...
by Edith Cowan University Credit: Pixabay/CC0 Public Domain Breast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer by the age of 85. Radiotherapy has emerged as an important component of breast cancer treatment but can lead to cancer-related fatigue and negatively impact...
