by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain Scientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for years after treatment. Inflammation is one possible culprit. A new long-term study of older breast cancer survivors published today in the Journal of Clinical Oncologyand co-led by UCLA researchers adds important...
by Emily Gersema, University of Southern California Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for Cancer Research, National Cancer Institute, National Institutes of Health A USC-led team of scientists has found indications that a special blood test called...
by Jane Langille, Cornell University Credit: Pixabay/CC0 Public Domain Weill Cornell Medicine investigators have identified definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC). Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients...
by National Physical Laboratory Credit: Unsplash/CC0 Public Domain Scientists at the UK’s National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue using an innovative new detection technique, which has the potential to significantly improve breast cancer outcomes by aiding in the earlier diagnosis and treatment of the disease. The technique works...
by Sarah Avery, Duke University Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111268 In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain. The finding, appearing online Aug. 30 in the journal Cell Reports, provides evidence for human trials and...
by Ananya Sen, University of Illinois at Urbana-Champaign Adam Nelczyk, left, and Erik Nelson have discovered that the nuclear receptor TLX can potentially be used to treat triple-negative breast cancer. Credit: Julia Pollack Adam Nelczyk, left, and Erik Nelson have discovered that the nuclear receptor TLX can potentially be used to treat triple-negative breast cancer....
by University of Ottawa Stage–specific distribution of female breast cancer cases, ages 40 to 49 years versus ages 50 to 59 years, Canada excluding Quebec, 2010 to 2017. Note: Quebec is excluded because cases diagnosed in Quebec from 2011 onward had not been submitted to the Canadian Cancer Registry. Vertical error bars indicate 95% confidence...
by Johns Hopkins University School of Medicine A triple-negative breast cancer organoid invades collagen tissue. Credit. Credit: Eloïse Grasset, Johns Hopkins Medicine Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that...
by Johannes Angerer, Medical University of Vienna Waterfall plot of responses in patients evaluable for response by RANO-BM criteria in the TUXEDO-1 trial. Blue bars illustrate the radiographic change of maximum brain metastasis size after start of trastuzumab deruxtecan therapy compared to the baseline measurement. Red dotted lines denote thresholds for response and progression by...
by National University of Singapore (a) Schematic representation of an assembled tES shell with surface pores for entry and exit of bioorthogonal catalysis substrates and products (left) and multilayer approach to bioorthogonal catalytic center cutaway (right). (b) Chemical products of IAA and their free radical derivatives. (c) Mass spectrometry of IAA products demonstrating catalytic specificity of...
