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Repairing broken brain circuits may offer path to new Parkinson’s treatments
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Repairing broken brain circuits may offer path to new Parkinson’s treatments

by Van Andel Research Institute SNc DA degeneration induces cell subtype–and input-specific alterations in M1.(A) Overall strategies to label projection defined M1 pyramidal neurons and optogentically activate thalamocortical transmission arising from the mTh. (B) Overlaid image showing the averaged AAV injection sites in the motor thalamus (left), as well as representative confocal images showing an...