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Too much of a good thing—persistent IFNγ depletes progenitor blood cells via BST2
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Too much of a good thing—persistent IFNγ depletes progenitor blood cells via BST2

by  Baylor College of Medicine Credit: CC0 Public Domain When a person has an infection, the body activates immune responses to fight it. IFNγ is an inflammatory molecule produced by the immune system that helps fight infections. However, long-term exposure to IFNγ has undesirable consequences—it irreversibly exhausts blood stem cells, the progenitors of all blood cells, including immune cells, by triggering their proliferation and excessive terminal...