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Scientists discover how mutations affect calcium release channel and impact muscle disorders
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Scientists discover how mutations affect calcium release channel and impact muscle disorders

September 18, 2024 by Juntendo University Research Promotion Center S5 mutations disrupt RyR1 channel function, influencing both channel activity and gating mechanisms. This impacts the release of calcium and affects muscle contractions, leading to severe muscle diseases such as malignant hyperthermia and central core disease. Credit: Associate Professor Takashi Murayama from Juntendo University, Japan and...