By Paul McClureOctober 15, 2023 DepositphotosA study has found that moderate calorie restriction can bolster the expression of healthy aging genesA study has found that moderate calorie restriction can bolster the expression of healthy aging genesA new study has investigated the biological mechanisms brought about by calorie restriction and found that a moderate reduction in...
Tag: <span>calorie restriction</span>
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Calorie restriction slows pace of aging in healthy adults
by Columbia University’s Mailman School of Public Health Credit: CC0 Public Domain In a first of its kind randomized controlled trial an international team of researchers led by the Butler Columbia Aging Center at the Columbia University Mailman School of Public Health shows that caloric restriction can slow the pace of aging in healthy adults....
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Calorie restriction trial reveals gene that may prolong healthy life
A new study investigates calorie restriction in humans. Catherine MacBride/Stocksy Laboratory studies have found that some animals on calorie-restricted diets live longer. Researchers are keen to find out whether there is a similar effect in people. Now, a small-scale study suggests that moderate calorie restriction may benefit human health. The researchers identified a key protein that might increase...
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Active phase calorie restriction enhances longevity, UT Southwestern neuroscience study reveals
UT SOUTHWESTERN MEDICAL CENTER IMAGE: JOSEPH TAKAHASHI, PH.D. CREDIT: UT SOUTHWESTERN MEDICAL CENTER A new study in mice led by neuroscientists at UT Southwestern’s Peter O’Donnell Jr. Brain Institute shows that it’s not just calories that count. Timing feedings to match the active period of the circadian cycle extended the life span of lab mice more than...
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Calorie restriction yields ‘remarkable’ health benefits that can lead to longer lifespan
FEBRUARY 22, 2022 by Faith Coleman Calorie restriction in laboratory animals enhances their lifespan, prior research shows, but does the same hold true for humans? Researchers at Yale University concluded the first controlled study of the dietary regimen in healthy humans to determine if it is indeed as beneficial for people. Results confirm that calorie...
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Calorie restriction trial reveals key factors in extending human health
by Yale University Credit: CC0 Public Domain Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear. Now a new study led by Yale researchers confirms the health benefits of...
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Calorie Restriction versus Cancer, Viewed in Terms of Growth Signaling
The practice of calorie restriction, eating fewer calories while still obtaining sufficient micronutrients, is well demonstrated to reduce cancer risk in animal models, and also appears to improve outcomes in the case of an established cancer. This is similarly the case for practices such as intermittent fasting or fasting mimicking diets, the latter having undergone trials as an adjuvant therapy...
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The Benefits of Calorie Restriction are Based on Calorie Intake, not Food Quantity
Researchers here note that reduction in the calorie content in the diet is the important trigger for the benefits of calorie restriction, not reductions in the quantity of food ingested. The practice of calorie restriction, reducing calorie intake while still obtaining optimal micronutrient intake, has been shown to extend life span in near all species and lineages tested to...
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Resveratrol is Not an Effective Calorie Restriction Mimetic
Resveratrol and derived molecules were for a time excessively hyped as a means to trigger some of the beneficial metabolic response produced by calorie restriction, by acting on sirtuins, and thus have a positive impact on aging. The company Sirtris was founded to develop this area of research into a therapeutic, its backers did a great deal to promote the aforementioned excessive hype, the...
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Can a drug mimic the life extending effects of calorie restriction?
A new study provides drug developers with clues about how to extend healthy lifespan without severely restricting calorie intake. Research is ongoing into a drug that can mimic the life extending effects of calorie restriction. Scientists have known for some time that restricting calorie intake in laboratory animals can extend their lifespan and reduce their risk...