Tag: <span>cancer-associated fibroblasts (CAFs)</span>

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Users of high-potency cannabis four times more likely to report associated problems
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Users of high-potency cannabis four times more likely to report associated problems

by University of Bristol Users of high-potency cannabis are four times more likely to report associated problems, and twice as likely to report anxiety disorder, than users of lower-potency strains, according to new research from the University of Bristol. Published today on JAMA Psychiatry the research uses data from Children of the 90s, a long-term...

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Telomere length prognostic in hepatocellular carcinoma

Li-Jie Ma, from Fudan University in Shanghai, and colleagues used telomere-specific fluorescence in situ hybridization and quantitative polymerase chain reaction to assess telomere length in HCC cell lines, tumor tissues, and nontumor cells within the tumor. The researchers found that, compared with their normal counterparts, significant telomere attrition was found in tumor cells and cancer-associated fibroblasts (CAFs), but...

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Single-cell analysis reveals subtypes of colorectal tumors

Cancer — Histopathologic image of colonic carcinoid.    Combining single-cell genomics and computational techniques, a research team including Paul Robson, Ph.D., director of single-cell biology at The Jackson Laboratory (JAX), has defined cell-type composition of cancerous cells from 11 colorectal tumors, as well as adjacent noncancerous cells, a key to more targeted diagnosis and treatment....