TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: ION-SENSITIVE FIELD EFFECT TRANSISTORS DETECT BREAST CANCER CELLS EXPRESSING EGFR WHEN BOUND BY AN ANTIBODY LINKED TO A CHEMICAL REPORTER CREDIT: DEPARTMENT OF BIOELECTRONICS, TMDU Researchers from Tokyo Medical and Dental University (TMDU) find that ion-sensitive field effect transistors can be combined with enzymatic chemical signal amplification to detect...
UNIVERSITY OF BONN IMAGE: THEREBY INHIBITING THE IMMUNE SYSTEM (LEFT). CERITINIB STOPS THE FORMATION OF ADENOSINE. ATP ACCUMULATES AND ACTIVATES IMMUNE CELLS (RIGHT). CREDIT: FIGURE: LAURA SCHÄKEL/UNIVERSITY OF BONN – CREATED WITH BIORENDER.COM Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can...
by Case Western Reserve University Human chromosomes (grey) are capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA Research published in Science Signaling identifies new ways that telomeres regulate the aggressiveness and survival of tumors, making them potentially vulnerable therapeutic targets for killing cancer. The discovery was made by a team of researchers at Case Comprehensive Cancer Center and Case Western Reserve School...
by Larner College of Medicine at the University of Vermont Image of a triple negative breast cancer cell undergoing abnormal division after inhibition of KIF18A (red = microtubules; green = chromosomes; yellow = spindle poles). Credit: Cindy Fonseca, M.S., Stumpff Lab, UVM Larner College of Medicine Unravelling the unique characteristics of cancer cells and finding...
By Leslie Nemo on January 29, 2021 Open Compilation of 3-D color-projection photographs of a cancer cell highlights its internal structures. The photography technique used to capture these images, called Z stacking, helps researchers see the contents of cells and where each part lies in relation to the others. Credit: Dylan T. Burnette and Aidan M. Fenix Despite the...
by Texas A&M University Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0 The first step in treating cancer is understanding how it starts, grows and spreads throughout the body. A relatively new cancer research approach is the study of metabolites, the products of different steps...
by Diamond Light Source Crystal structure of LMTK3 – graphic adapted from Science Advances Paper see paper DOI: 10.1126/sciadv.abc3099 for full description. An international study led by scientists at the University of Sussex has provided strong evidence for an effective new target for breast cancer treatment. The five-year study, called “The structure-function relationship of oncogenic LMTK3,”...
Posted by Kathleen Hoffman Something unusual happened when Professor Andrew Sewell and the T-Cell Modulation Group at the University of Cardiff put the blood of a healthy donor in a petri dish with some cancer cells. What grew in the blood was a T-cell that no one had seen before. This T-cell attacked the cancer cells...
A mechanism that enables cancer cells to scavenge dead cell debris for nourishment may lead to new ways to overcome drug resistance, a new study shows. Drug resistance remains a major challenge in the fight against cancer. “Cancer cells require a tremendous amount of nutrients,” says Aimee Edinger, professor of developmental and cell biology at...
by The Korea Advanced Institute of Science and Technology (KAIST) A novel approach to reverse the progression of healthy cells to malignant ones may offer a more effective way to eradicate colorectal cancer cells with far fewer side effects, according to a team of researchers based in South Korea. Colorectal cancer, or cancer of the...
