MAY 16, 2024 by Netherlands Cancer Institute Organoid of a patient with colon cancer, treated (right) and not treated with the chemotherapy etoposide. The treatment causes DNA damage and a reduction in protein synthesis. This triggers a stress signal that causes the cells to die. Orange: marker for DNA damage. Green: marker for protein synthesis....
by Rachel Sauer, CU Anschutz Medical Campus Credit: CC0 Public Domain Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes. Mutations in tumor suppressor genes can allow tumors to grow unchecked—a case of no brakes—while mutations in oncogenes can activate cell proliferation,...
by University of Notre Dame Zachary Schafer working in the lab. Credit: University of Notre Dame One specific protein may be a master regulator for changing how cancer cells consume nutrients from their environments, preventing cell death and increasing the likelihood the cancer could spread, a study from the University of Notre Dame has shown. The...
