MAX-PLANCK-GESELLSCHAFT IMAGE: CARTOON REPRESENTATION OF THE POLRMT-INHIBITOR COMPLEX. CREDIT: HAUKE S. HILLEN A newly developed compound starves cancer cells by attacking their “power plants” – the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing in Cologne, the Karolinska Institute...
by Goethe University Frankfurt am Main In glioblastoma cells, the antidiarrheal drug loperamide triggers the degradation of the endoplasmic reticulum. In the normal state, it is coloured yellow in these microscopic images. In the degradation state, it glows as a red signal (marked with arrows). Left scale bar: 20 µm, right scale bar (inset): 5 µm....
by KU Leuven New research has shown that the antidepressant sertraline inhibits the growth of cancer cells. It acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals performed by various research labs of KU Leuven. Their findings were published in Molecular Cancer Therapeutics, a journal...
By Nick Lavars, October 27, 2020 Golden nanotubes can be seen in green making their way into the cancer cell Tiny nanoscale materials offer unique properties, and one way scientists are looking to leverage these is by taking aim at cancer cells of different kinds. A research team in the UK have demonstrated how an adaptation of...
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE IMAGE: MAXIMILIANO D’ANGELO, PH.D., ASSOCIATE PROFESSOR IN THE DEVELOPMENT, AGING AND REGENERATION PROGRAM AT SANFORD BURNHAM PREBYS. Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes–large channels that control the flow of materials in and out of the cell nucleus–shrank aggressive tumors...
NANYANG TECHNOLOGICAL UNIVERSITY IMAGE: (LEFT TO RIGHT) MEMBERS OF THE NTU RESEARCH TEAM INCLUDE ASSISTANT PROFESSOR DALTON TAY FROM THE SCHOOL OF MATERIALS SCIENCE AND ENGINEERING, RESEARCH ASSOCIATE KENNY WU AND ASSOCIATE PROFESSOR TAN NGUAN SOON FROM NTU’S LEE KONG CHIAN SCHOOL OF MEDICINE. Cancer cells are killed in lab experiments and tumour growth reduced...
JOHNS HOPKINS MEDICINE IMAGE: CANCER CELLS WITH EXCESS CENTROSOMES. DNA IS SHOWN IN BLUE, AND CENTROSOMES ARE SHOWN AS GREEN AND RED. Scientists at Johns Hopkins Medicine and the University of Oxford say they have found a new way to kill some multiplying human breast cancer cells by selectively attacking the core of their cell...
A new type of immunotherapy for the skin cancer malignant melanoma shows promising results. Three severely ill patients are now long-term survivors. The study, published in OncoImmunology, is the result of a collaboration between researchers at Karolinska Institutet and Karolinska University Hospital. “Immunotherapy is based on activation of the body’s own immune defense to eliminate...
by Chinese Academy of Sciences Gastric cancer is the third leading cause of cancer death worldwide, accounting for over 1,000,000 new cases and nearly 800,000 deaths per year. The poor prognosis of gastric cancer is largely due to the difficulty in early diagnosis of peritoneal metastasis. Separation and characterization of cancer cells are essential for...
INNOVATION CENTER OF NANOMEDICINE LEFT: HYDROPHOBIC EPIRUBISIN IS CONJUGATED TO ONE END OF HYDROPHILIC POLYETHYLENE GLYCOL (PEG) CHAIN WITH ASPARTATE-HYDRAZIDE AS A LINKER. IN WATER, THIS MOLECULE IS SELF-ASSEMBLED TO FORM NANO-MICELLES (EPI/M). UPPER… view more CREDIT: 2020 INNOVATION CENTER OF NANOMEDICINE Summary: A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the...
