by Curtin University New Curtin University-led research has discovered that using drugs to target a pathway in the body that causes cancerous cells to spread aggressively may help to reduce the severity of bladder cancer. The research, published in Nature Communications, aimed to understand the function of two naturally occurring proteins called hepatocyte growth factor...
Tag: <span>cancer cells</span>
Research Identifies Proteins Responsible for Cancer Spreading
Posted Yesterday Advances in the sciences have made it easier than ever to live with and survive various kinds of cancer. One of the lingering challenges that remains is metastasis, or the ability of cancer cells to migrate to new pathological sites within the host’s body. October is National Breast Cancer Awareness Month. Too many...
Repurposing heart drugs to target cancer cells
by MRC London Institute of Medical Sciences Senescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has revealed that senescent cells play important roles in a growing list of diseases from cancer, to arthritis, atherosclerosis and many more. Previous studies have shown that...
A compound effective to chemotherapy-resistant cancer cells identified
HOKKAIDO UNIVERSITY A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. Despite longstanding and earnest endeavors to develop new remedies, the prognosis of most glioblastoma patients undergoing chemotherapies and radiotherapies remains poor. Glioblastoma, a malignant glioma, has a median...
Scientists have identified the presence of cancer-suppressing cells in pancreatic cancer
by Nagoya University A research team led by Nagoya University has revealed that cells containing a protein called Meflin have a role in restraining the progression of pancreatic cancer, a type of cancer that is hard to treat with traditional anti-cancer drugs. The team has also shown that cancer progression can be limited by artificially...
Scientists discover the structure of cancer molecule
By Maria Cohut Fact checked by Jasmin Collier Alternative splicing is a complex but insufficiently understood process. It is crucial to the production of proteins necessary to cell health. Researchers now believe that cancer cells also use this process to their own advantage. Proteins are large molecules that are absolutely crucial to the health of every single...
Liquid biopsy chip detects tumor cells in 100 percent of blood samples from breast cancer patients
by Michael W. Dorsey, Worcester Polytechnic Institute Researchers at Worcester Polytechnic Institute (WPI) have developed a chip made of carbon nanotubes that can capture circulating tumor cells (CTCs) of all sizes and types, and can do so with far greater sensitivity than existing technologies. The unique design of the device makes it possible to easily...
Coating immune cells in nanoparticles helps seek and destroy rogue cancer cells
Michael Irving One of the main reasons cancer can be so difficult to beat is because of its ability to spread through the body, even after the primary tumor has been surgically removed. But now researchers from Vanderbilt University have developed a new technique that uses nanoparticles to enhance immune cells, helping them hunt down...
Study ties unhealthy gums to liver cancer risk
By Catharine Paddock PhD Fact checked by Isabel Godfrey A large study of people living in the United Kingdom found that those who reported having poor oral health, such as sore or bleeding gums or loose teeth, had a 75% higher risk of developing liver cancer. Previous studies have already established that gums and teeth that are...
Drug-resistant cancer cells create own Achilles heel
by Nicole Giese Rura, Whitehead Institute for Biomedical Research The cells of most patients’ cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing proteasome inhibitors have failed. Now scientists may have solved the mystery of these cells’ surprising hardiness....