NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: IMAGE SHOWING THE PREPARATION OF HYDROGELS THAT ENHANCE THE VIABILITY OF NK CELLS CREDIT: KOREA INSTITUTE OF MACHINERY AND MATERIALS (KIMM) A three-dimensional (3D) bioprinting technology capable of eliminating cancer cells using the function of immune cells has been developed for the first time in the world. Through joint...
by Anna Megdell, University of Michigan Profiling of metabolite utilization in PDA cells identifies uridine. Credit: Nature (2023). DOI: 10.1038/s41586-023-06073-w Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings, published in...
By Michael Franco April 27, 2023 The new technique allows a very precise level of surgery that doesn’t damage surrounding tissue Created by The Hospital for Sick Children (SickKids) research team using Midjourney When it comes to fighting the deadly brain cancer known as glioblastoma, options are very much limited. This led a Canadian research team to...
by University College London 3D Extravasation assay for probing mechanics of cancer cells, endothelium, and the underlying ECM. a) Schematic representation of the extravasation assay. b) Quantification of the permeability of the HUVECs monolayer (magenta) formed on top of a thin collagen substrate. The permeability was calculated by measuring the changes of 70 kDa dextran (green) intensity...
by German Cancer Research Center Credit: Pixabay/CC0 Public Domain A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this oxidation, cells switch to an alternative sugar breakdown pathway and can thus escape oxidative stress. Cancer cells...
Jumping genes are short sections of DNA that have been incorporated randomly into the human genome over the long course of evolution. Also called transposable elements, these pieces of DNA have been implicated in cancer development. But new research from Washington University School of Medicine in St. Louis suggests that potentially transposable elements in various cancers...
by American Society for Biochemistry and Molecular Biology Researchers engineered immune cells (NK-92) to anchor glycocalyx-editing (GE) enzymes on the surface. The modified immune cells were able to break through the glycocalyx armor of cancer cells. Credit: Sangwoo Park, Cornell University One of the ways that cancer cells hide from the body’s immune system is...
UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES For the first time, a research team has identified and analyzed the steps by which immune cells “see” and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others. The UCLA Jonsson Comprehensive Cancer Center scientists leading the research believe their findings will lead...
by Christopher Vaughan, Stanford University Medical Center Credit: Unsplash/CC0 Public Domain Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer—altering cancer cells so that they teach the body’s immune system to fight the very cancer the cells came from. “This approach could...
by University of Technology, Sydney The Static Droplet Microfluidic device. Credit: Dr. Majid Warkiani Researchers from the University of Technology Sydney have developed a new device that can detect and analyze cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress. Cancer is a leading cause of illness and...
