By CALIFORNIA INSTITUTE OF TECHNOLOGY JULY 8, 2022 An artist’s depiction of a bacterial cell. Credit: Centers for Disease Control and Prevention/James Archer Since its inception, chemotherapy has proven to be a valuable tool in treating many kinds of cancers, but it has a significant drawback. In addition to killing cancer cells, it can also destroy healthy...
by Columbia University Credit: Unsplash/CC0 Public Domain Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth. The research, led by Dennis Vitkup, Ph.D., associate professor of systems biology at...
by Max Delbrück Center for Molecular Medicine Integration of multiple datasets enables robust extraction of informative gene sets. A, B ikarus workflow. ikarus is a two-step procedure for classifying cells. In the first step, integration of multiple expert labeled datasets enables the extraction of robust gene markers. The gene markers are then used in a...
JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE IMAGE: FIRST AUTHOR, ALBERTO BUENO-COSTA AND CHIEF SUPERVISOR, DR. MANEL ESTELLER CREDIT: JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE Barcelona, June 9th, 2022. A new research describes how highly proliferative leukemia cells end up becoming normal cells that no longer multiply, by changing the chemical modifications -the so-called epigenetics- of a type of...
by Institute of Cancer Research USP25 is highly expressed and enzymatically active in PDAC compared to normal pancreatic tissue, which correlated with poor patient survival. a Histological and immunohistochemical analysis of Usp25 expression in normal pancreatic and KPCY tumor tissues. Scale bar is 100 µm. b Quantification of Usp25 positive staining area (n = 6 biologically independent animals...
By Nick Lavars April 27, 2022 A new study has demonstrated how star-shaped devices can be introduced into cells and cause their demise CSIC The field of nanomedicine is progressing rapidly and in recent years has opened up all kinds of exciting possibilities, with scientists showing how tiny particles could be deployed to deliver drugs, fight inflammation and prevent...
by Bob Yirka, Medical Xpress Credit: Science (2022). DOI: 10.1126/science.abl3855 A team of researchers from Genetch, Inc., the Howard Hughes Medical Institute and the Peter MacCallum Cancer Center, has found that cancerous tumor cells are able to survive attacks by repairing holes in their membranes caused by a protein released from T cells. In their paper published...
by Emma Rose Johnson, Rush University Medical Center Prostate cancer cells. Credit: NIH Image Gallery Prostate cancer affects one in every eight men during their lifetime, making it the most prevalent form of cancer for males. For many, the standard of care means facing aggressive treatments that include radiation and the freezing or removal of...
by Greta Friar, Whitehead Institute for Biomedical Research Credit: Jennifer Cook-Chrysos/Whitehead Institute Cancer is at its most deadly when it spreads and forms tumors in new tissues. This process, called metastasis, is responsible for the vast majority of cancer deaths, and yet there is still a lot that researchers do not know about how and...
MEDICAL COLLEGE OF WISCONSIN IMAGE: IMAGE: ADVANCED MRI SHOWS A 93% REDUCTION IN CONTRAST ENHANCING TUMOR VOLUME (T1+C: YELLOW ARROW) IN ONE RAT RESPONDING TO GAM TREATMENT. IB’S QUANTITATIVE DELTA T1 (ΔT1) MAPS ALLOW VISUALIZATION OF “TRUE” TUMOR ENHANCEMENT FREE OF CONFOUNDING BLOOD PRODUCTS. IB’S RELATIVE CEREBRAL BLOOD VOLUME (RCBV) NOTICEABLY DECREASED BY DAY 50...
