By Pete Farley Plitidepsin was 27.5-fold more potent against SARS-CoV-2 than remdesivir, a drug that received FDA emergency use authorization in 2020 for the treatment of COVID-19, according to new research. Image by NIH Scientists at UC San Francisco’s Quantitative Bioscience Institute (QBI) and the Icahn School of Medicine at Mt. Sinai (ISMMS) in New York have shown that plitidepsin...
Upon entry into our cells, SARS-CoV-2 immediately gets to work replicating itself. The process is nothing short of impressive: A suite of enzymes and proteins work to copy the virus’s genetic material into thousands of more copies, wrapping each in proteins and lipids, and ultimately sending them bursting out of the cell-like confetti from a...
by Stanford University Stanford virologist Jeffrey Glenn did not set out to tackle cancer. For years, he and his lab have worked to develop new ways of battling viruses like the ones that cause hepatitis delta and the common cold—but the lessons they’ve learned fighting viruses has led to a new kind of drug that...
UNIVERSITY OF EDINBURGH The painful symptoms of endometriosis – a chronic condition which affects millions of women – could potentially be reduced with a drug that had previously been investigated as a cancer treatment. Researchers found that using dichloroacetate to treat the cells of women with endometriosis lowered the production of lactate – a potentially...
OCTOBER 7TH, 2019 SIAVASH PARKHIDEH MEDICINE, ONCOLOGY Researchers from the City University of Hong Kong have developed a new, controllable cancer drug called phorbiplatin that only becomes active and potent after red light stimulation. Their work demonstrates that in the dark the cancer drug does not have substantial toxicity, but the drug is able to...
INSTITUTE OF CANCER RESEARCH A new type of drug that blocks one of cancer’s key evolutionary escape routes from chemotherapy could be used to treat aggressive breast cancers, a new study has shown. Scientists at The Institute of Cancer Research, London, found that the drug could reinvigorate the response to chemotherapy in cancers that had...
Posted Today The newest cancer treatment on the market owes something to one of the earliest advocates for modern science. In his work Novum Organum, which is widely credited with introducing the scientific method, Francis Bacon wrote of the need for creative thinking to achieve anything new, saying that it would be a mistake, “to expect that things which...
Michael Irving There are several techniques used to kill cancer, such as chemotherapy and radiotherapy, but the really tricky part is doing so without harming the rest of the body. Cytokines are small proteins that could play a part in immunotherapy, but they’ve so far not been approved for use, given their toxicity to healthy...
For Bridgett Snelten, changing her health insurance meant enduring wild blood sugar swings, bouts of vomiting and weight gain. The Sandy, Utah mother of two young girls has diabetes and has had to change health insurance plans three years in a row. Twice, new insurers wouldn’t cover Trulicity, a once-a-week injected diabetes medicine she’d been...
Duncan Hunter chokes up a little when it is suggested that work he began at Western three decades ago will now, finally, be applied to saving hundreds of lives. “It’s a good thing,” said the Chemistry professor emeritus after a long pause. “It took 30 years and had its ups and downs. So, yes, it’s...
