by Institute of Cancer Research Study design and number of samples per tumor type included in the analysis. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01785-9 Researchers have carried out an in-depth analysis of 10,478 cancer genomes across 35 different cancer types, identifying 330 potential cancer-driving genes, 74 of which are newly associated with cancer. The findings highlight the potential...
Tag: <span>cancer genes</span>
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Detects cancer genes with ultra-high sensitivity!
MultimediaRelease 6-Sep-2024 The Korea Institute of Materials Science(KIMS) has developed the world’s most sensitive technology for detecting cancer mutant genes in blood Peer-Reviewed PublicationNational Research Council of Science & Technology image: Representative diagram of 3D nanoplasmonics-based technology for detecting mutant genes in blood Credit: Korea Institute of Materials Science (KIMS) Dr. Min-young Lee and Dr....
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Large, diverse genetic study of glaucoma implicates vascular and cancer-related genes
by Vanderbilt University Medical Center Credit: CC0 Public DomainAn international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally. The findings, published in Cell Reports Medicine, detail ancestry- and sex-specific genetic loci associated with POAG...
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Identifying cancer genes’ multiple personalities
by Cold Spring Harbor Laboratory An up-close look at a mouse’s liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz’s lab. Credit: Beyaz lab/Cold Spring Harbor Laboratory Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations...
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New opportunities for targeting overactive cancer genes
by Karolinska Institutet Fig. 1: The CTCFBS within the OSE-specific eRNA gene (CCAT1) confers a proliferative advantage to the HCT-116 cells. a The position of the CCAT1-specific CTCFBS within the OSE is indicated (black arrow). The core binding sequence was modified at 8 bases, as marked by gray boxes in the panel, by CRISPR editing....