by Anne Trafton, Massachusetts Institute of Technology This image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachusetts Institute of Technology Stimulating the body’s immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies...
WAKE FOREST BAPTIST MEDICAL CENTER IMAGE: DAWEN ZHAO, M.D., PH.D., ASSOCIATE PROFESSOR OF BIOMEDICAL ENGINEERING AT WAKE FOREST SCHOOL OF MEDICINE, AND TEAM HAVE DISCOVERED THAT A NANOPARTICLE THERAPEUTIC ENHANCES CANCER IMMUNOTHERAPY AND IS A POSSIBLE NEW APPROACH IN TREATING MALIGNANT PLEURAL EFFUSION (MPE). CREDIT: WAKE FOREST SCHOOL OF MEDICINE WINSTON-SALEM, N.C. – Dec. 16,...
by Thomas Jefferson University Credit: CC0 Public Domain A class of cancer immunotherapy called checkpoint inhibitors has revolutionized cancer treatment. It’s a new way to attack the disease by unleashing the immune system. However, not every patient benefits from the treatment, and it can cause severe, sometimes life-threatening, side effects in some. New research shows...
by Memorial Sloan Kettering Cancer Center Scanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIH To an immunologist, autoimmune diseases like Type 1 diabetes are the polar opposite of cancer. In the former, the immune system goes into overdrive and attacks the body’s own organs in a relentless manner, eventually causing disease;...
by Chinese Academy of Sciences Preparation of macrophage–tumor chimeric exosomes and tumor inhibition mechanism. Credit: WEI Wei Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy. Their study was published in Science Translational Medicine on Oct....
by Hokkaido University After intravenous injection into mice, STING-lipid nanoparticles (red) transported through blood vessels (green) accumulate in the liver. Credit: Takashi Nakamura, et al. Journal for ImmunoTherapy of Cancer. July 2, 2021 Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for...
by Johns Hopkins University School of Medicine The molecular data types studied with respect to patient age in cancer. Credit: Bioender A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger...
by The Francis Crick Institute Dendritic cells are white blood cells that get their name from their tree-like shape. Credit: The Francis Crick Institute Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein...
by Kyoto University Cancer cell during cell division. Credit: National Institutes of Health Cancer immunotherapies have made the news for their startling effectiveness against certain cancers. However, current clinical therapies mainly use the patient’s own cells, limiting the number of patients who have access to this cure. CiRA Professor Shin Kaneko is developing iPS cells technology...
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN A team of researchers has found disrupting the interaction between cancer cells and certain immune cells is more effective at killing cancer cells than current immunotherapy treatments. The findings, which include studies in cell lines and animal models, appeared in JCI Insight and focus on a protein called CD6 as a target for a...
