Tag: <span>Cancer Immunotherapy</span>

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Study finds increased risk of cancer death following treatment for hyperthyroidism

by  National Cancer Institute Findings from a study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer. The study, led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, was published July...

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New approach to Cancer Immunotherapy overcomes toxicity hurdle

In an effort to develop more effective cancer treatments, scientists are looking for therapies that supercharge patients’ immune systems. One possibility is to use antibodies that activate CD40, an immune-cell protein that, when triggered, prompts the rest of the immune system to spring into action. Credit: CC0 Public Domain Though promising, drugs that target CD40...

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Cytokine levels could predict autoimmune reactions to cancer Immunotherapy

The development of immunotherapy, which mobilizes the body’s own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients. Researchers at UT Southwestern have identified blood-based biomarkers that may help identify those patients at greatest risk of developing autoimmune...

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Woman’s late-stage breast cancer cured by immunotherapy treatment that supercharged her own cells to fight the disease in a world first

Immunotherapy enhances a patient’s own T cells to make them fight cancer better  Doctors at the National Institutes of Health have cured a woman of her breast cancer using the experimental new treatment   A woman has been cured of her breast cancer by a revolutionary treatment that used supercharged versions of her own immunity cells...

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The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy

The microbiome is receiving significant attention given its influence on a host of human diseases including cancer. Its role in response to cancer treatment is becoming increasingly apparent, with evidence suggesting that modulating the gut microbiome may affect responses to numerous forms of cancer therapy. A working knowledge of the microbiome is vital as we...

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Researchers Build a Cancer Immunotherapy Without Immune Cells

Conceptual illustration of a designer cell sensing a target cell Engineering an immune cell to recognize and kill a cancer cell is the key to chimeric antigen receptor (CAR) T-cell therapy, but modified immune cells also have the potential to cause problems for patients. One such complication, cytokine release syndrome, is an overreaction of the immune...

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Cancer immunotherapy may work better in patients with specific genes

Cancer cells arise when DNA is mutated, and these cells should be recognized as “foreign” by the immune system. However, cancer cells have found ways to evade detection by the immune system. New drugs called immune checkpoint inhibitors can restore the immune system’s recognition of cancer cells and have led to dramatic responses in a...

December 19, 2017December 19, 2017by In Cancer
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Scientists discover possible master switch for programming cancer immunotherapy

Study authors Adam Getzler, Dapeng Wang and Matthew Pipkin of The Scripps Research Institute collaborated with scientists at the University of California, San Diego.    During infection or tumor growth, a type of specialized white blood cells called CD8+ T cells rapidly multiply within the spleen and lymph nodes and acquire the ability to kill...

December 12, 2017December 12, 2017by In Cancer