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How sound waves trigger immune responses to cancer in mice
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How sound waves trigger immune responses to cancer in mice

by University of Michigan Histotripsy ablation is followed by infiltration of innate and adaptive immune cell populations. Mice bearing bilateral B16F10 tumors were treated with unilateral sham (control) or partial histotripsy ablation on day 10. Multicolor immunofluorescence performed 1, 3 and 10 days after sham or histotripsy partial histotripsy ablation revealed (A) early infiltration of...

Tiny, implantable therapeutic sponge device helps kill cancer in mice
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Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis, University of California, Los Angeles The SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), which suppress the body’s response to solid tumors. At the same time, the SymphNode’s microparticles (black dots) attract and beef up cancer-fighting T cells. Credit: Negin...