CITY UNIVERSITY OF HONG KONG IMAGE: MICROFLUIDIC CHIPS DESIGNED AND FABRICATED BY THE TEAM TO MIMIC THE IN VIVO ENVIRONMENT. CREDIT: © CITY UNIVERSITY OF HONG KONG Cancer metastasis is a major cause of cancer-related death. A research team at City University of Hong Kong (CityU)recently identified a protein that triggers the migration of liver...
Tag: <span>Cancer Metastasis</span>
Link between sphingolipids and complement signaling may be key to stopping cancer metastasis
by Caroline Wallace, Medical University of South Carolina Graphical Abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111742 MUSC Hollings Cancer Center researchers have identified the sequence of molecular interactions that could be key to stopping the spread of cancer cells. Currently, there is no reliable therapeutic approach to prevent metastasis, the leading cause of death from solid cancerous tumors. Published...
Researchers identify drug characteristics that make cancer metastasis therapy more effective
by Tohoku University Optimal osmotic pressure and viscosity ranges for anticancer drug solvents used in lymphatic delivery (blue area). It is applicable to all types of cancer. Credit: Tohoku University Cancer is an umbrella term for diseases characterized by the uncontrollable growth of tumor cells. Often, these tumor cells invade and colonize adjoining organs, giving...
Handheld photoacoustic finder for diagnosing cancer metastasis without radiation
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: DIAGRAM OF A HANDHELD PHOTOACOUSTIC FINDER SYSTEM CREDIT: POSTECH Massaging the upper arm is known to relieve the body of swelling by stimulating the lymph nodes that process toxins in our body. Cancers such as breast cancer and melanoma metastasize primarily through lymphatic system, so knowing the...
Cell couriers deliver clue to cancer metastasis
UNIVERSITY OF WARWICK IMAGE: INTEGRINS BEING MOVED INSIDE A MIGRATING CELL. INTEGRINS APPEAR AS DARK SPOTS, CELL NUCLEUS IS BLUE. CREDIT: MÉGHANE SITTEWELLE, UNIVERSITY OF WARWICK A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University...
The mRNA alphabet: Identification of a new mechanism to cancer metastasis
by Université libre de Bruxelles Credit: Unsplash/CC0 Public Domain When cancers metastasize, cells from the primary tumor break away, travel through the blood or lymph system and form new tumors in other body parts. Although metastasis is responsible for more than 90% of all cancer deaths, limited progress has been made in treating cancers that have...
Study reveals how Y-box binding protein 1 promotes cancer metastasis
by Li Yuan, Chinese Academy of Sciences YB1 triggers cell invasion and cancermetastasis by regulating the miRNA200/205b-ZEB axis. Credit: LIU Xiumei and CHEN Di Metastasis of cancer is the main cause of cancer relevant death as well as the main challenge of cancer treatment. Recently, a group led by Prof. Piao Hailong from the Dalian Institute...
Team discovers new organelle involved in cancer metastasis
by Liz Fuller-Wright, Princeton University This 3D image of human breast cancer bone metastases shows the formation of the newly described organelle (magenta) in cancer cells (cyan). Cell nuclei from both cancer cells and normal bone cells are labeled in blue. Credit: Image rendering by Mark Esposito and Gary Laevsky Some of Princeton’s leading cancer researchers were startled...
Blocking tumor signals can hinder cancer’s spread
by University of Pennsylvania For most people who die of cancer, the spread of the initial tumor is to blame. “Metastasis is what kills most cancer patients,” says Serge Fuchs, a professor in Penn’s School of Veterinary Medicine. “Yet there are not many, if any, drugs that specifically target metastatic processes.” In a paper in...
Shape-shifting stem cells are key to cancer metastasis and immune evasion
MEMORIAL SLOAN KETTERING CANCER CENTER Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don’t one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells. Cancer cells, on the other hand, are like perpetual...
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