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New protein complex structure reveals possible ways to target key cancer pathway
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New protein complex structure reveals possible ways to target key cancer pathway

by Alex Viveros,  Broad Institute of MIT and Harvard The SHOC2-MRAS-PP1C complex is made up of three proteins that regulate the RAS signaling pathway and help cancer cells with RAS mutations survive. Credit: Broad Institute and Dana-Farber Cancer Institute Some of the most infamous drivers of cancer are mutations in RAS genes, which lead to tumor...