by Delthia Ricks, Medical Xpress Schematic of histological quantification of the dense inner colonic mucus layer histologically, following PAS staining. Eight equally radially spaced sites are identified for mucus layer thickness quantification which are then averaged for each sample. Credit: Science Translational Medicine (2022). DOI: 10.1126/scitranslmed.abo3445 An altered gut microbiome is an unexpected cause of fever afflicting...
by University of Tsukuba Credit: create jobs 51/Shutterstock Providing prognostic information is a vital component of cancer patient care. However, the specific information cancer patients prefer to receive has been poorly understood, which can impact patient satisfaction and the quality of doctor-patient communications. Now, researchers in Japan have revealed that cancer patients prefer to be...
NATIONAL COMPREHENSIVE CANCER NETWORK IMAGE: JNCCN COVER, OCTOBER 2022 CREDIT: NCCN PLYMOUTH MEETING, PA [October 17, 2022] — New research published in the October 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network confirms the safety of mRNA vaccines in people with cancer undergoing immunotherapy treatment. The researchers analyzed the frequency of side effects...
by Johannes Angerer, Medical University of Vienna Baseline cardiovascular toxicity risk assessment checklist. BNP, B-type natriuretic peptide; cTn, cardiac troponin; CTR-CVT, cancer therapy-related cardiovascular toxicity; CV, cardiovascular; CVD, CV disease; CVRF, cardiovascular risk factors; ECG, electrocardiogram; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; NT-proBNP, N-terminal pro-BNP; TTE, transthoracic echocardiography. Including blood pressure, heart rate,...
by Johannes Angerer, Medical University of Vienna Receptor-Binding Domain and Angiotensin-Converting Enzyme 2 Interaction Inhibition in Patients With Hematologic Malignant Neoplasm With or Without B Cell–Targeting Treatment Nominal P values without correction for multiple testing were calculated using Wilcoxon signed-rank test. Bars represent the IQR, whiskers represent the 25th/75th percentile ± 1.5x IQR, and horizontal...
TEL-AVIV UNIVERSITY IMAGE: FROM LEFT TO RIGHT: PROF. HELENA FLORINDO, PROF. RONIT SATCHI-FAINARO, DR. RITA ACÚRCIO, PROF. RITA GUEDES CREDIT: ERIC SULTAN & UNIVERSITY OF LISBON. Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an...
by Umea University AURKB is ubiquitinated in different cancers and forms a complex with TβRI in prostate cancer. (a) In situ PLA was performed on TMAs to investigate the co-localization of AURKB and K63-linked ubiquitin (brown dots). The numbers of normal prostates, kidneys, and lungs were 22, 24, and 23, respectively. The numbers of prostate...
by European Association of Urology Credit: Unsplash/CC0 Public Domain Researchers who treated a group of post-surgery bladder cancer patients with the immunotherapy drug atezolizumab have found that patients whose blood contained circulating tumor DNA (ctDNA), responded very well to the treatment. The study is presented today at the European Association of Urology annual congress (EAU22),...
FRONTIERS A comprehensive assessment of the benefits of medical cannabis for cancer-related pain found that for most oncology patients, pain measures improved significantly, other cancer-related symptoms also decreased, the consumption of painkillers was reduced, and the side effects were minimal. Published in Frontiers in Pain Research, these findings suggest that medicinal cannabis can be carefully considered...
by Global Alliance for Genomics and Health Credit: Pixabay/CC0 Public Domain Too many women are getting unnecessary mastectomies and other invasive procedures because of a knowledge gap about differences in cancer genes. A new study offers a path to closing the gap. Nearly a decade ago, Angelina Jolie made famous that preventative mastectomies can help...
