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In the lab: T cells artificially endowed with 2 cancer-seeking receptors aim to be an elite army of cancer killers
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In the lab: T cells artificially endowed with 2 cancer-seeking receptors aim to be an elite army of cancer killers

by Delthia Ricks, Medical Xpress Figure S1. Design of chimeric antigen receptor (CAR) and chimeric costimulatory receptor (CCR) constructs and expression of CAR, CCR, and CD38 on T cells. (A) Schematic diagrams of the vectors used for CARs and CCRs are shown. SP, signal peptide; P2A, “self-cleaving” 2A peptide; IC, intracellular domain; TM, transmembrane domain....