INNOVATION CENTER OF NANOMEDICINE Innovation Center for NanoMedicine (iCONM; Center Director: Prof. Kazunori Kataoka), a research institute of the Kawasaki Institute of Industrial Promotion (KIIP), has announced that a group led by Prof. Horacio Cabral (Visiting Scientist of iCONM / Associate Professor of Bioengineering, Graduate School of Engineering, University of Tokyo) discovered a new way to improve...
Tag: <span>cancer resistance</span>
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Drug combo breaks down cancer resistance to immunotherapy
by Ecole Polytechnique Federale de Lausanne A schematic summary of the study. Credit: Douglas Hanahan (EPFL) Immunotherapy is a way of treating cancer by reprogramming the patient’s immune system to attack their tumor. This cutting-edge approach has significantly impacted the treatment of cancer patients, and already boasts cases of long-term remission. Nonetheless, many patients either...
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A new understanding of cancer resistance to treatment
by University of Kent Credit: Pixabay/CC0 Public Domain New research has revealed the differences in mechanism behind cancer’s resistance to the major class of anti-cancer drugs known as nucleoside analogs. Nucleosides are molecules containing the genomic information that can be chemically modified into so-called nucleoside analogs to cause them to inhibit DNA formation in cancer cells, causing the...
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Blocking a protein could help overcome cancer resistance to PARP inhibitors
by The Francis Crick Institute Micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/Wikipedia Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead...