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Small molecule drug reverses ADAR1-induced cancer stem cell cloning capacity
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Small molecule drug reverses ADAR1-induced cancer stem cell cloning capacity

by University of California – San Diego A colorized scanning electron micrograph depicts human red blood cells. Credit: UC San Diego Health Sciences Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an...

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‘Labyrinth’ Chip Could Help Monitor Aggressive Cancer Stem Cells

ANN ARBOR–Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial. Tumor cells isolated from blood samples have the...

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First of its kind cancer stem cell research unlocks clues to treatment resistance

Researchers at Trinity College Dublin have made exciting new findings that could offer a means of fighting resistance to treatment for people with esophageal cancer. Resistance to radiotherapy is a major stumbling block in the treatment of this cancer. For the first time, the research team led by Dr Stephen Maher, Ussher Assistant Professor in...