Tag: <span>Cancer</span>

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A New Cancer Treatment Has Given Terminal Patients a Second Chance at Life

IN BRIEF Gene therapy has been shown in clinical trials to not just treat cancer, but possibly cure it. The treatments have risks — including death — so additional research is needed before they could become widely available. COULD THIS TREATMENT CURE CANCER? Despite the many advances in medicine over the last century, a cure...

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Here’s How Google’s AI Helps Detect Cancer Via Deep Learning

Deep learning, a form of artificial intelligence (AI) where computers are taught to recognize patterns in huge datasets, can now be useful in identifying breast cancer. Google reported March 3, Friday, that it has achieved groundbreaking results in using AI to analyze thousands of cancer cell slides from a Dutch university and diagnose the common form...

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New treatment causes cancer cells to fill up with cellular ‘trash’ and self-destruct

The genomes of cancer cells—cells that do not obey signals to stop reproducing—are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins. Like all other cells, cancer cells need to be vigilant about cleaning themselves up in order to survive. Now, biologists in the laboratory of Ray Deshaies, Caltech professor of biology...

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Salmonella 'can kill cancer': How bacteria that cause food poisoning could be used to attack tumour cells

A genetically-altered form of salmonella is being developed to combat cancer It would kill off the tumour cells while leaving the healthy cells alone  The new strain would also help the body’s immune system target tumours  The bacteria that cause food poisoning could be used to kill cancer, medical experts said yesterday. A genetically-altered form of...

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The Principles of Engineering Immune Cells to Treat Cancer

Chimeric antigen receptor (CAR) T cells have proven that engineered immune cells can serve as a powerful new class of cancer therapeutics. Clinical experience has helped to define the major challenges that must be met to make engineered T cells a reliable, safe, and effective platform that can be deployed against a broad range of tumors. The...

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Applications of Immunogenomics to Cancer

Cancer immunogenomics originally was framed by research supporting the hypothesis that cancer mutations generated novel peptides seen as “non-self” by the immune system. The search for these “neoantigens” has been facilitated by the combination of new sequencing technologies, specialized computational analyses, and HLA binding predictions that evaluate somatic alterations in a cancer genome and interpret...

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Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

Introduction Metastatic cancers remain an incurable disease for the great majority of patients, as the intrinsic genomic instability common to all cancers facilitates the escape from cytotoxic or targeted therapies. The recent breakthroughs in the understanding of tumor immune biology and the development of newer generation of cancer immunotherapies have opened a brand new chapter...