JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY IMAGE: A VERSATILE LIQUID METAL (LM) GALLIUM-INDIUM ALLOY HAS BEEN USED TO DEVELOP A NOVEL LM NANOPARTICLE THAT HARBORS AN IMMUNOMODULANT AND AN IMMUNE CHECKPOINT INHIBITOR, ANTI-PD-L1. UPON IRRADIATION BY NEAR INFRA-RED LIGHT, ANTI-PD-L1 SPECIFICALLY BINDS TO THE CANCER CELL, WHILE IMMUNOSTIMULANTS ACTIVATE T AND DENDRITIC CELLS. THIS...
UNIVERSITÉ LIBRE DE BRUXELLES Metastases and resistance to chemotherapy are the main causes of treatment failure and mortality in cancer patients. Epithelial-mesenchymal transition (EMT), a process by which cancer cells detach from their neighboring cells and acquire invasive properties, plays a key role in the formation of metastases and the development of resistance to anti-cancer...
by Chinese Academy of Sciences Strategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer. Credit: MENG Jiaqi Based on non-invasive, easy-to-manipulate near-infrared (NIR) laser irradiation, researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and the University of the Chinese Academy of...
WYSS INSTITUTE FOR BIOLOGICALLY INSPIRED ENGINEERING AT HARVARD IMAGE: THE RESEARCHERS VISUALIZED THE CELL-PERMEABLE POROUS STRUCTURE OF AN INJECTABLE SIVET IMMUNO-MATERIAL USING SCANNING ELECTRON MICROSCOPY ANALYSIS (SEM). CREDIT: WYSS INSTITUTE AT HARVARD UNIVERSITY By Benjamin Boettner (BOSTON) — Cancer immunotherapy has brought major improvement in patient survival and quality of life, especially with the success...
By Paul McClure July 05, 2023 A study has found that an energy-producing nutrient is key to maintaining the body’s cancer-destroying immune responseDepositphotos VIEW 1 IMAGES New research has discovered that a fundamental nutrient found in cells is key to maintaining the body’s cancer-destroying immune response. The discovery may lead to more effective ways of...
By Nicholas Florko July 13, 2023 MATT ROURKE/AP WASHINGTON — Aspartame, the popular artificial sweetener in diet sodas and chewing gums, may possibly cause cancer — but the risk appears to be very low for occasional consumers of these products, according to two reports released Thursday evening by the World Health Organization. The first report, penned by...
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS A new study published in the Journal of the National Cancer Institute brings researchers and oncologists one step closer to better understanding the complexities of PD-1 inhibitors, a common type of immunotherapy, and their intracellular signaling on cancer behavior. Until recently, cancer intrinsic PD-L1 signaling has been only partially reported in...
By Carolyn Y. JohnsonJuly 6, 2023 at 2:00 p.m. EDT Researchers using modern gene-editing tools have discovered that the intuition of scientists from more than a century ago was right: Cells with unusual numbers of chromosomes are drivers of cancer. The study, published Thursday in the journal Science, renews scientific attention on an old-fashioned idea, one that could point...
by University of California – San Diego Mouse pancreatic tumors were significantly smaller after being treated with a combination of KRAS inhibitor MRTX1133 and ERBB inhibitor Afatinib (bottom row), compared to no treatment (top row) or being treated with Afatinib (second row) or MRTX1133 (third and fourth rows) alone. Credit: UC San Diego Health Sciences Mutations...
COLD SPRING HARBOR LABORATORY IMAGE: IN MICE WITH PANCREATIC AND COLORECTAL CANCER, KETO DIETS SLOW THE GROWTH OF TUMORS, SEEN HERE IN WHITE, BY A PROCESS CALLED FERROPTOSIS. THIS KILLS THE CANCER CELLS BY CAUSING A LETHAL BUILDUP OF TOXIC FATTY MOLECULES, STAINED RED Dietitians say a keto diet could help you lose up to...
