What is ablation technology? Ablation therapy consists of a minimally invasive treatment, which can be used for treating cancer by destroying tumors and other abnormal tissues within the body. It uses either extremely high or low temperatures to remove a layer or layers of tissue. However, radiofrequency energy or electrical currents can also be used.1...
Tag: <span>Cancer</span>
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Discovery of key gene offers new hope in treating chronic myeloid leukemia
Schematic image, showing the R-loop resolution by REXO5 (left) and the inhibition of R-loop resolution by REXO5 mutation (right). Credit: Leukemia (2024). DOI: 10.1038/s41375-024-02362-z A key gene that could enhance the treatment success rates of chronic myeloid leukemia (CML) has been discovered by researchers. Professor Hongtae Kim and his research team in the Department of Biological Sciences...
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Promising cell therapy offers hope for relapsed or refractory T-cell leukemia
Antileukemia activity of anti-CD7 PEBL-CAR T cells. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-03228-8 A new cell therapy, targeting CD7 in leukemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukemia (T-ALL) who have exhausted all standard treatment options. Published in the journal Nature Medicine on 3 September 2024, the study highlights the effectiveness of a new chimeric...
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Early blood test can predict survival in men newly diagnosed with metastatic prostate cancer, clinical trial finds
A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest. It can help providers decide which patients should receive standard treatment versus who might stand to benefit from riskier, more aggressive new drug trials. The research, part of a Phase...
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Scientists discover that special immune cells stop metastatic cancer
Metastatic disease—when cancer spreads from the primary tumor to other parts of the body—is the cause of most cancer deaths. While researchers understand how cancer cells escape the primary site to seed new tumors, it’s not well understood why some of these wayward cancer cells spawn new tumors—sometimes decades later—while others do not. Now, a...
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Cancer biologists discover the drug, 5-fluorouracil, acts differently in different types of cancer
Since the 1950s, a chemotherapy drug known as 5-fluorouracil has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed that this drug works by damaging the building blocks of DNA. However, a new study from MIT has found that in cancers of the...
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Uterine cancer rates are increasing: What can you do to protect yourself?
Uterine cancer is the most common type of gynecologic cancer. It’s estimated that about 67,880 new cases will be diagnosed in 2024. Approximately 13,250 people will die from this disease in the U.S. in 2024, according to the National Cancer Institute. Researchers recently reported that while death rates for the most common type of uterine cancer—endometrioid cancer—remained stable, deaths from...
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Innovative model using CRISPR provides valuable insights into prostate cancer spread
September 23, 2024 by Weill Cornell Medical College Abstract representation of the cancer clonal landscapes in different places in the body, revealing the different clonal architectures. The lines represent some of the trajectories of metastatic cells as they traverse the body. Credit: American Association for Cancer ResearchA new preclinical model using CRISPR, an advanced technology...
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The viruses that can give you cancer. Experts now say one in five cancer-related deaths could be triggered by an illness
By Pat Hagan Published: 07:00 EDT, 19 September 2024 | Updated: 08:09 EDT, 19 September 2024 Quit smoking, go easy on the alcohol and stick to a healthy diet. For years, this has been the mantra for reducing our risk of cancer, a disease that now affects one in two of us at some point...
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Proto-Oncogene Activation: The Genetic Shift that Fuels Cancer
By Dr. Priyom Bose, Ph.D.Reviewed by Danielle Ellis, B.Sc. Proto-oncogenes are a group of genes that normally regulate cell division and growth by encoding regulator proteins for cell cycle, growth factors, transcription factors, DNA-binding proteins, and protein kinases that are involved in signal transduction. Upon mutation, proto-oncogenes change to oncogenes and transform normal cells into...