by University of Tokyo Graphical abstract. Credit: Nucleic Acids Research (2023). DOI: 10.1093/nar/gkad1164Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic view that cis-regulatory elements (CREs) are mere on/off switches for genes, emphasizing their ability to exhibit complex...
Discovery opens window to more effective treatment Peer-Reviewed Publication UNIVERSITY OF CALIFORNIA – RIVERSIDE THE MYC PROTEINS (GREY RIBBONS) BIND TO DNA AND PROMOTE CANCER PROGRESSION. UCR RESEARCHERS DEVELOPED A MOLECULE (ORANGE PRETZEL-LIKE SHAPE) THAT BINDS TO MYC, INHIBITING ITS CANCER-PROMOTING FUNCTION. CREDIT: MIN XUE/UCR Meet MYC, the shapeless protein responsible for making the majority...
By Paul McClure Researchers have harnessed the cancer-destroying abilities of the body’s natural killer cells Depositphotos Researchers have made a breakthrough in cancer treatment by harnessing the disease-destroying abilities of the body’s natural killer cells. Their novel nanodrones selectively target a tumor, enabling the killer cells to do what they do best: Suppress cancer growth. The...
Angela Speth, MD In our Western diet, dairy and beef are ubiquitous: Milk goes with coffee, melted cheese with pizza, and chili with rice. But what if dairy products and beef contained a new kind of pathogen that could infect you as a child and trigger cancer or multiple sclerosis (MS) 40-70 years later? Researchers...
by Delthia Ricks , Medical Xpress Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy. Mobilizing the immune system to destroy cancers has...
by Jason Howland, Mayo Clinic News Network Credit: Unsplash/CC0 Public Domain The holidays are a joyous occasion for most people. But for someone with cancer or other serious illness, it can be a time of overwhelming anxiety and fear. And as family and friends get together, it’s important to show that you care without coming...
by Wiley Credit: CC0 Public Domain Results from a Phase II clinical trial indicate that psilocybin, a hallucinogenic chemical found in certain mushrooms of the genus Psilocybe, may benefit individuals with cancer and major depression. Trial participants treated with psilocybin not only experienced a lessening of depressive symptoms but also spoke highly of the therapy when...
by Delthia Ricks , Medical Xpress N6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (C) Effects of N6F11 on the growth of 3D PANC1 tumor spheroids for increasing...
by Werner Siefer, Paul Scherrer Institute Overview of our platform to study the chromatin organization of peripheral blood mononuclear cells in a tumor and proton therapy setting. Credit: npj Precision Oncology (2023). DOI: 10.1038/s41698-023-00484-8 The ability to detect a developing tumor at a very early stage and to closely monitor the success or failure of cancer...
by UT Southwestern Medical Center Illustration of using Ceograph for pathology image classification. a Flowchart of traditional image classification (upper arrow) and Ceograph (bottom arrow). The Ceograph method includes nuclei identification through HD-Staining, graph construction, and classification. The application to lung cancer histology subtype classification is used as an example. The image patches are 1024 × 1024 pixels...
