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Researchers discover molecular fail-safe that keeps bladder tissues from turning cancerous
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Researchers discover molecular fail-safe that keeps bladder tissues from turning cancerous

by Fred Hutchinson Cancer Center Credit: Pixabay/CC0 Public Domain Over the decades, scientists have revealed many strategies our cells use to keep normal cells from becoming cancerous. Now, Fred Hutchinson Cancer Center scientists have discovered a completely new—and counterintuitive—emergency brake that bladder cells use to stave off tumors even when cancer-promoting genes are turned on. In...

Breakthrough in study of how epithelial cells become cancerous
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Breakthrough in study of how epithelial cells become cancerous

OSAKA UNIVERSITY IMAGE: MOLECULAR MECHANISM OF ESCAPE FROM APICAL EXTRUSION DURING CELL COMPETITION. CREDIT: 2022 KAJIWARA ET AL., SRC ACTIVATION IN LIPID RAFTS CONFERS EPITHELIAL CELLS WITH INVASIVE POTENTIAL TO ESCAPE FROM APICAL EXTRUSION DURING CELL COMPETITION , CURRENT BIOLOGY Osaka, Japan – Epithelial cells, which line the surfaces and organs of the body, can...

Changes can be detected in BRCA1 breast cells before they turn cancerous
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Changes can be detected in BRCA1 breast cells before they turn cancerous

Researchers may have found the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear, according to a new study published in the journal Nature Communications. The study, funded by Cancer Research UK, showed that before becoming cancerous, breast cells with the BRCA1 gene mutation undergo changes similar to those normally seen in late pregnancy....

Antioxidant-rich foods like black tea, chocolate, and berries may increase risk for certain cancers, new study finds
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Antioxidant-rich foods like black tea, chocolate, and berries may increase risk for certain cancers, new study finds

by Hebrew University of Jerusalem It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to attract cancer?...

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Leukaemia cells can transform into non-cancerous cells through epigenetic changes

by Manel Esteller and Alberto Bueno-Costa, Josep Carreras Leukaemia Research Institute Researchers of the Josep Carreras Leukaemia Research Institute discover that a leukaemic cell is capable of transforming into a non-cancerous cell through epigenetic changes. All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects. For example, a lymphocyte and a neuron share...