September 23, 2024 by University of Dundee Credit: Unsplash/CC0 Public DomainExperts from the University of of Dundee’s Centre for Targeted Protein Degradation (CeTPD), working with Boehringer Ingelheim scientists, have developed a breakthrough small-molecule drug, a “protein degrader.” KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions...
September 15, 2024 by University of Texas M. D. Anderson Cancer Center Credit: Unsplash/CC0 Public DomainTreatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD...
by Will Cushman, University of Wisconsin-Madison This image shows the effect of pro-inflammatory cytokines on the growth of a mouse intestinal organoid. Intestinal stem cells (red) are indicative of inflammation and Ki67 proteins (green) are associated with tumors. Credit: Ting FuInflammation in the gut can trigger a doom loop of sorts. The condition messes with the...
by University of Texas M. D. Anderson Cancer Center Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA vaccine has shown potential to prevent relapse of KRAS-mutated pancreatic and colorectal cancers for patients who had previously undergone surgery, according to a Phase I trial led by researchers at The...
by QIMR Berghofer Integrative analysis of samples from patients with AML. a, Unsupervised hierarchical clustering analysis on the expression of 300 transcripts with the greatest variance-to-mean ratios among 30 individual AMLs from our repository that can successfully generate AML PDX. MLD, multi-lineage dysplasia; MDS, myelodysplastic syndromes; MLL, mixed-lineage leukemia; NOS, not otherwise specified. b, Key...
Experts say regular exercise is an effective way to reduce your risk of cancer. Danil Nevsky/Stocksy Researchers are reporting that good cardiovascular fitness can help reduce the risk of nine types of cancer, including lung, liver and rectal cancer. They say the risk reduction is between 5% and 42% for these various cancers. Experts say...
By Michael Irving May 09, 2023 Scientists have discovered a new cause of cancer – a mutation in a specific gene that interferes with a cellular cleanup process Depositphotos Cancer can be the end result of a wide range of things that go wrong, and understanding how is key to prevention and treatment. Now, scientists...
By Hank Berrien•May 1, 2023 Peter Dazeley/GettyImages A new study indicates that an artificial intelligence tool can tremendously improve predictions of whether a nodule will develop cancer, thereby helping identify cancer much earlier in deadly diseases such as lung cancer. Experts at the Royal Marsden NHS foundation trust, the Institute of Cancer Research, London, and Imperial...
by New York University Structure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same pocket as ATP. Credit: Traaseth Lab/NYU More than 70 FDA-approved cancer drugs are kinase inhibitors, which work by blocking kinases—enzymes that...
Roxanne Nelson, RN, BSN December 20, 2022 Currently, guidelines recommend screening for only four types of cancer, and adherence to the guidelines is often low. Nnevertheless, screening tests lead to diagnoses of about 14% of all cancers in the United States, a new study suggests. Screening is currently recommended for breast, cervical, colorectal, and lung cancers by...
